Journal ArticleDOI
A meta-analysis of cognitive deficits in first-episode Major Depressive Disorder.
Rico S.C. Lee,Rico S.C. Lee,Daniel F. Hermens,Melanie A. Porter,M. Antoinette Redoblado-Hodge +4 more
TLDR
The current meta-analysis was the first to systematically demonstrate reduced neuropsychological functioning in first-episode Major Depressive Disorder.About:
This article is published in Journal of Affective Disorders.The article was published on 2012-10-01. It has received 593 citations till now. The article focuses on the topics: Psychomotor learning & Major depressive disorder.read more
Citations
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Journal ArticleDOI
Major depressive disorder
Christian Otte,Stefan M. Gold,Stefan M. Gold,Brenda W.J.H. Penninx,Carmine M. Pariante,Amit Etkin,Maurizio Fava,David C. Mohr,Alan F. Schatzberg +8 more
TL;DR: An overview of the current evidence of major depressive disorder, including its epidemiology, aetiology, pathophysiology, diagnosis and treatment, is provided.
Journal ArticleDOI
Cognitive impairment in depression: a systematic review and meta-analysis
TL;DR: It is argued that remediation of cognitive impairment and alleviation of depressive symptoms each play an important role in improving outcome for patients with depression, and cognitive impairment represents a core feature of depression that cannot be considered an epiphenomenon that is entirely secondary to symptoms of low mood.
Journal ArticleDOI
Cognitive deficits and functional outcomes in major depressive disorder: determinants, substrates, and treatment interventions.
Roger S. McIntyre,Danielle S. Cha,Joanna K. Soczynska,Hanna O. Woldeyohannes,Laura Ashley Gallaugher,Paul Kudlow,Mohammad Alsuwaidan,Anusha Baskaran,Anusha Baskaran +8 more
TL;DR: Few reports have aimed to describe the mediational effect of cognitive deficits on functional outcomes in major depressive disorder, and relatively few interventions are demonstrated to mitigate cognitive deficits in MDD.
Journal ArticleDOI
Frailty and cognitive impairment--a review of the evidence and causal mechanisms.
TL;DR: The evidence for an association between frailty and cognitive impairment is reviewed and some of the mechanisms that potentially underpin this relationship from brain neuropathology and hormonal dysregulation to cardiovascular risk and psychological factors are outlined.
Journal ArticleDOI
Cognitive impairment in euthymic major depressive disorder: a meta-analysis
TL;DR: Cognitive deficits overall appear to be more common among patients with late-onset depression, supporting the theories suggesting that possible vascular and neurodegenerative factors play a role in a substantial number of these patients.
References
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Journal ArticleDOI
Measuring inconsistency in meta-analyses
TL;DR: A new quantity is developed, I 2, which the authors believe gives a better measure of the consistency between trials in a meta-analysis, which is susceptible to the number of trials included in the meta- analysis.
Journal ArticleDOI
Bias in meta-analysis detected by a simple, graphical test
TL;DR: Funnel plots, plots of the trials' effect estimates against sample size, are skewed and asymmetrical in the presence of publication bias and other biases Funnel plot asymmetry, measured by regression analysis, predicts discordance of results when meta-analyses are compared with single large trials.
Book
Statistical Methods for Meta-Analysis
Larry V. Hedges,Ingram Olkin +1 more
TL;DR: In this article, the authors present a model for estimating the effect size from a series of experiments using a fixed effect model and a general linear model, and combine these two models to estimate the effect magnitude.
Journal ArticleDOI
Statistical Methods for Meta-Analysis.
TL;DR: In this paper, the authors present a model for estimating the effect size from a series of experiments using a fixed effect model and a general linear model, and combine these two models to estimate the effect magnitude.