Ben J. Harrison

TL;DR: In this article, the authors present the largest ever worldwide study by the ENIGMA (Enhancing Neuro Imaging Genetics through Meta-Analysis) Major Depressive Disorder Working Group on cortical structural alterations in MDD.

TL;DR: This study directly supports the hypothesis that OCD is associated with functional alterations of brain corticostriatal networks, as measured from coherent spontaneous fluctuations in the blood oxygenation level-dependent signal.

TL;DR: Functional MRI is used to characterize functional interactions between the default mode network and different EAS components during performance of a recollection task known to coactivate regions of both networks and shows that increased cooperation between the DMN and a specific right-lateralized frontoparietal component of the EAS is associated with more rapid memory recollection.

TL;DR: A comprehensive meta-analysis of human fear-conditioning studies carried out with functional magnetic resonance imaging (fMRI), yielding a pooled sample of 677 participants from 27 independent studies, demonstrates that human fear conditioning is associated with a consistent and robust pattern of neural activation across a hypothesized genuine network of brain regions resembling existing anatomical descriptions of the ‘central autonomic–interoceptive network’.

TL;DR: Cognitive deficits overall appear to be more common among patients with late-onset depression, supporting the theories suggesting that possible vascular and neurodegenerative factors play a role in a substantial number of these patients.