Journal ArticleDOI
Frailty and cognitive impairment--a review of the evidence and causal mechanisms.
TLDR
The evidence for an association between frailty and cognitive impairment is reviewed and some of the mechanisms that potentially underpin this relationship from brain neuropathology and hormonal dysregulation to cardiovascular risk and psychological factors are outlined.About:
This article is published in Ageing Research Reviews.The article was published on 2013-09-01. It has received 508 citations till now. The article focuses on the topics: Cognitive decline & Dementia.read more
Citations
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Journal ArticleDOI
Frailty: implications for clinical practice and public health.
Emiel O. Hoogendijk,Jonathan Afilalo,Kristine E. Ensrud,Paul Kowal,Graziano Onder,Linda P. Fried +5 more
TL;DR: An overview of the global impact and burden of frailty, the usefulness of the frailty concept in clinical practice, potential targets for frailty prevention, and directions that need to be explored in the future are provided.
Journal ArticleDOI
2018 ESC Guidelines for the diagnosis and management of syncope.
Michele Brignole,Angel Moya,Frederik J. de Lange,Jean-Claude Deharo,Perry M. Elliott,Alessandra Fanciulli,Artur Fedorowski,Raffaello Furlan,Rose Anne Kenny,Alfonso Martín,Vincent Probst,Matthew J. Reed,Ciara Rice,Richard Sutton,Andrea Ungar,J. Gert van Dijk +15 more
TL;DR: Authors/Task Force Members: Michele Brignole* (Chairperson), Angel Moya* (Co-chairperson) (Spain), Frederik J. de Lange (The Netherlands), Jean-Claude Deharo (France), Perry M. Elliott (UK), Alessandra Fanciulli (Austria), Artur Fedorowski (Sweden), Raffaello Furlan (Italy), Rose Anne Kenny (Ireland), Alfonso Mart ın (Spain
Journal ArticleDOI
Effectiveness of interventions to prevent pre-frailty and frailty progression in older adults: a systematic review.
João Apóstolo,Richard Cooke,Elzbieta Bobrowicz-Campos,Silvina Santana,Maura Marcucci,Antonio Cano,Miriam Marie Rosé Vollenbroek-Hutten,Federico Germini,Barbara D'Avanzo,Holly Gwyther,Carol Holland +10 more
TL;DR: There is mixed results regarding the effectiveness of frailty interventions, but there is clear evidence on the usefulness of such interventions in carefully chosen evidence-based circumstances, both for frailty itself and for secondary outcomes, supporting clinical investment of resources in frailty intervention.
2018 ESC Guidelines for the diagnosis and management of syncope
TL;DR: In this paper, Brignole, Moya, and van Dijk proposed a task force for gender equality in the workplace, with the task force's chairperson Michele Bignole and co-chairmen Angel Moya and Jean-Claude Deharo.
Journal ArticleDOI
Frailty as a Risk Factor for Falls Among Community Dwelling People: Evidence From a Meta-Analysis
Mei-Hsun Cheng,Shu-Fang Chang +1 more
TL;DR: It is confirmed that compared with robust older adults, frail older adults were more likely to experience recurrent falls, and older adults should be evaluated for the possibility of geriatric syndromes such as frailty, which may be addressed to reduce the risk for bone fractures and death.
References
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Journal ArticleDOI
Frailty in Older Adults Evidence for a Phenotype
Linda P. Fried,Catherine M. Tangen,Jeremy D. Walston,Anne B. Newman,Calvin H. Hirsch,John S. Gottdiener,Teresa E. Seeman,Russell P. Tracy,Willem J. Kop,B Gregory Burke,Mary Ann McBurnie +10 more
TL;DR: This study provides a potential standardized definition for frailty in community-dwelling older adults and offers concurrent and predictive validity for the definition, and finds that there is an intermediate stage identifying those at high risk of frailty.
Journal Article
Cardiovascular Health Study Collaborative Research Group : Frailty in older adults : evidence for a phenotype
Journal ArticleDOI
Broken Limits to Life Expectancy
Jim Oeppen,James W. Vaupel +1 more
TL;DR: The evidence presented in this paper suggests that the apparent leveling off of life expectancy in various countries is an artifact of laggards catching up and leaders falling behind, not a sign that life expectancy is approaching its limit.
Journal ArticleDOI
Frailty in Relation to the Accumulation of Deficits
TL;DR: Although based on a simple count, the frailty index shows several interesting properties, including a characteristic rate of accumulation, a submaximal limit, and characteristic changes with age in its distribution.
Journal ArticleDOI
Gait speed at usual pace as a predictor of adverse outcomes in community-dwelling older people an International Academy on Nutrition and Aging (IANA) Task Force
Gabor Abellan van Kan,Yves Rolland,Sandrine Andrieu,Juergen M. Bauer,Olivier Beauchet,Marc Bonnefoy,Matteo Cesari,Lorenzo M. Donini,Sophie Gillette-Guyonnet,Marco Inzitari,Fati Nourhashemi,Graziano Onder,P. Ritz,Antoni Salvà,Marjolein Visser,Bruno Vellas +15 more
TL;DR: Gait speed at usual pace was found to be a consistent risk factor for disability, cognitive impairment, institutionalisation, falls, and/or mortality in older adults as mentioned in this paper, and the use of simple, safe, and easy to perform assessment tool, like gait speed, to evaluate vulnerability to adverse outcomes in community-dwelling older people is appealing.
Related Papers (5)
Frailty Consensus: A Call to Action
John E. Morley,Bruno Vellas,G. Abellan Van Kan,Stefan D. Anker,Juergen M. Bauer,Roberto Bernabei,Matteo Cesari,Wm. Cameron Chumlea,Wolfram Doehner,Jonathan Evans,Linda P. Fried,Jack M. Guralnik,Paul R. Katz,Theodore K. Malmstrom,Roger McCarter,Luis Miguel Francisco Gutierrez Robledo,Kenneth Rockwood,Stephan von Haehling,Maurits Vandewoude,Jeremy D. Walston +19 more