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Open AccessJournal ArticleDOI

A multicenter study on the effects of lanthanum carbonate (Fosrenol) and calcium carbonate on renal bone disease in dialysis patients.

TLDR
LC is a poorly absorbed, well-tolerated, and efficient phosphate binder in dialysis patients, who show almost no evolution toward low bone turnover over one year (unlike CC-treated patients), nor do they experience any aluminum-like effects on bone.
About
This article is published in Kidney International.The article was published on 2003-06-01 and is currently open access. It has received 320 citations till now. The article focuses on the topics: Renal osteodystrophy & Lanthanum carbonate.

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Citations
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Renal osteodystrophy

汪关煜
Journal ArticleDOI

Oral phosphate binders in patients with kidney failure.

TL;DR: The rationale for treatment with oral phosphate binders is reviewed, evidence supporting the use of available agents is discussed, and an approach for clinical practice is suggested.
Journal ArticleDOI

Renal osteodystrophy in the first decade of the new millennium: Analysis of 630 bone biopsies in black and white patients

TL;DR: Bone biopsies from adult CKD‐5 patients on dialysis were evaluated by histomorphometry and analyzed using the turnover (T), mineralization (M), and volume (V) classification; there were racial differences; whites exhibited predominantly low turnover, whereas blacks showed mostly normal or high turnover.
References
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Journal ArticleDOI

Coronary-Artery Calcification in Young Adults with End-Stage Renal Disease Who Are Undergoing Dialysis

TL;DR: Coronary-artery calcification is common and progressive in young adults with end-stage renal disease who are undergoing dialysis who are undergoing dialysis.

Coronary-artery calcification in young adults with end-stage renal disease who are undergoing dialysis

TL;DR: In this paper, the authors used electron-beam computed tomography (CT) to screen for coronary-artery calcification in 39 young patients with end-stage renal disease who were undergoing dialysis (mean [±SD] age, 19±7 years; range, 7 to 30).
Journal ArticleDOI

Sevelamer attenuates the progression of coronary and aortic calcification in hemodialysis patients.

TL;DR: Compared with calcium-based phosphate binders, sevelamer is less likely to cause hypercalcemia, low levels of PTH, and progressive coronary and aortic calcification in hemodialysis patients.
Journal ArticleDOI

Re-evaluation of risks associated with hyperphosphatemia and hyperparathyroidism in dialysis patients: Recommendations for a change in management

TL;DR: It is shown that the current treatment paradigm for serum phosphorus and secondary hyperparathyroidism is ineffective for a large segment of dialysis patients, and it is believed that prevention of uremic calcification, cardiac death, and vascular disease should assume primary importance when evaluating the risks associated with elevated levels of phosphorus, CaxP, and PTH.
Book

Handbook on metals in clinical and analytical chemistry

TL;DR: The role of metals in clinical chemistry collection, transport, and storage of biological samples for the determination of trace metals method evaluation, quality control and external quality assurance systems of analytical procedures spectrophotometry atomic absorption spectrometry ion-selective electrodes as discussed by the authors.
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