A new coronavirus-like particle associated with diarrhea in swine
Maurice Pensaert,P. de Bouck +1 more
TLDR
Coronavirus-like particles were detected by electron microscopy in the intestinal contents of pigs during a diarrheal outbreak on 4 swine breeding farms, which was found to be distinct from the known porcine coronaviruses, transmissible gastroenteritis virus and hemagglutinating encephalomyelitis virus.Citations
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A decade after SARS: strategies for controlling emerging coronaviruses
TL;DR: The emergence and identification of novel human coronaviruses over the past 10 years are described, their key biological features are discussed, including tropism and receptor use, and approaches for developing broadly effective vaccines are summarized.
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Porcine epidemic diarrhoea virus: a comprehensive review of molecular epidemiology, diagnosis, and vaccines.
Daesub Song,Bong-Kyun Park +1 more
TL;DR: The molecular and genetic characteristics of the porcine epidemic diarrhoea virus are described, its molecular epidemiology and diagnosis, what vaccines are available, and how PEDV can be treated are discussed.
Journal ArticleDOI
Origin, Evolution, and Genotyping of Emergent Porcine Epidemic Diarrhea Virus Strains in the United States
Yao-Wei Huang,Yao-Wei Huang,Allan W. Dickerman,Pablo Piñeyro,Long Li,Li Fang,Ross Kiehne,Tanja Opriessnig,Tanja Opriessnig,Xiang-Jin Meng +9 more
TL;DR: The finding that the emergent U.S. PEDV strains share unique genetic features at the 5′-untranslated region with a bat coronavirus provided further support of the evolutionary origin of P EDV from bats and potential cross-species transmission.
Journal ArticleDOI
Bats and Coronaviruses.
TL;DR: This review follows the CoV outbreaks that are speculated to have originated in bats and reviews studies that have allowed researchers to identify unique adaptation in bats that may allow them to harbor CoVs without severe disease.
Journal ArticleDOI
Reverse genetics with a full-length infectious cDNA of severe acute respiratory syndrome coronavirus
Boyd Yount,Kristopher M. Curtis,Elizabeth A. Fritz,Lisa E. Hensley,Peter B. Jahrling,Erik Prentice,Mark R. Denison,Thomas W. Geisbert,Ralph S. Baric +8 more
TL;DR: Using a panel of contiguous cDNAs that span the entire genome, the authors have assembled a full-length cDNA of the SARS-CoV Urbani strain, and have rescued molecularly cloned SARS viruses (infectious clone SARS -CoV) that contained the expected marker mutations inserted into the component clones.
References
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The isolation of reovirus-like agents (rotaviruses) from acute gastroenteritis of piglets (Plates XVI)
TL;DR: It is concluded that the pig rotavirus is commonly associated with outbreaks of gastroenteritis and is probably an important aetiological factor in this disease.
Journal Article
A Hemagglutinating Virus Producing Encephalomyelitis in Baby Pigs.
TL;DR: In each case a cytopathogenic microorganism markedly different to the enteroviruses previously described has been isolated and proved to be hemagglutinating viruses and were shown to be pathogenic for baby pigs.
Journal ArticleDOI
Pleomorphic virus-like particles in human faeces.
TL;DR: Pleomorphic fringed particles bearing some resemblance to orthomyxoviruses and coronaviruses were seen in 90% ofStools from south Indian children and adults but not in stools from neonates, which may be related to the abnormalities of intestinal structure and function common in this region of India.
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