Journal ArticleDOI
A new method for receptor autoradiography: [3H]opioid receptors in rat brain.
W. Scott Young,Michael J. Kuhar +1 more
TLDR
The distribution of [3H]diprenorphine binding sites determined by this in vitro method is identical to the distribution found in earlier studies utilizing in vivo labeling of opioid receptors.About:
This article is published in Brain Research.The article was published on 1979-12-28. It has received 780 citations till now. The article focuses on the topics: Diprenorphine & Opioid peptide.read more
Citations
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Cellular and molecular mechanisms of drug dependence.
George F. Koob,Floyd E. Bloom +1 more
TL;DR: The molecular and cellular actions of three classes of abused drugs--opiates, psychostimulants, and ethanol--are reviewed in the context of behavioral studies of drug dependence.
Journal ArticleDOI
Hypothalamic Integration: Organization of the Paraventricular and Supraoptic Nuclei
Journal ArticleDOI
Acidic amino acid binding sites in mammalian neuronal membranes: their characteristics and relationship to synaptic receptors
Alan C. Foster,Graham E. Fagg +1 more
TL;DR: An evaluation of investigations designed to elucidate regulatory mechanisms at acidic amino acid binding sites is made; hypotheses such as the Ca2+-activated protease hypothesis of long-term potentiation are assessed in terms of the new binding site/receptor classification scheme.
Journal ArticleDOI
Distribution of α2 agonist binding sites in the rat and human central nervous system: Analysis of some functional, anatomic correlates of the pharmacologic effects of clonidine and related adrenergic agents
TL;DR: These functional, anatomical and neurochemical correlates of the alpha 2 binding site distribution establish a neurological basis for the complex pharmacological effects of centrally acting alpha 2 agonists.
Journal ArticleDOI
Serotonin receptors in the human brain--IV. Autoradiographic mapping of serotonin-2 receptors.
TL;DR: The anatomical distribution of serotonin-2 receptors in the human brain was studied by light microscopic autoradiography, using [3H]ketanserin as a ligand and the receptor densities were quantified by microdensitometry with the aid of a computer-assisted image-analysis system.
References
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Journal ArticleDOI
Connections of the cerebral cortex. I. The albino rat. A. Topography of the cortical areas
Journal ArticleDOI
Autoradiographic localization of opiate receptors in rat brain. I. Spinal cord and lower medulla.
Samir F. Atweh,Michael J. Kuhar +1 more
TL;DR: In these brain regions, opiate receptors are highly associated with areas receiving small, afferent primary fibers, strategically placed to modulate noxious stimuli as well as explain some visceral side effects of opiate administration.
Journal ArticleDOI
Multiple opiate receptors. Enkephalins and morphine bind to receptors of different specificity.
K J Chang,P Cuatrecasas +1 more
Journal ArticleDOI
Autoradiographic localization of opiate receptors in rat brain. II. The brain stem.
Samir F. Atweh,Michael J. Kuhar +1 more
TL;DR: The distribution of opiate receptors, determined by the autoradiographic localization of stereospecific [3H]diprenorphine binding sites, was studied in the brain stem and associations of some receptors with small diameter axons, pupillary reflexes, hormonal control, and effects of opiates on neurotransmitter systems were discussed.
Related Papers (5)
Light microscopic localization of brain opiate receptors: a general autoradiographic method which preserves tissue quality
Miles Herkenham,Candace B. Pert +1 more