Journal ArticleDOI
A prospective, population-based epidemiologic study of status epilepticus in Richmond, Virginia
Robert J. DeLorenzo,W. A. Hauser,Alan R. Towne,J. G. Boggs,John M. Pellock,L. Penberthy,L.K. Garnett,C. A. Fortner,Daijin Ko +8 more
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Evaluation of the seizure types for adult and pediatric patients demonstrated that both partial and generalized status epilepticus occur with a high frequency in these populations.Abstract:
This report presents the initial analysis of a prospective, population-based study of status epilepticus (SE) in the city of Richmond, Virginia. The incidence of SE was 41 patients per year per 100,000 population. The frequency of total SE episodes was 50 per year per 100,000 population. The mortality rate for the population was 22%, 3% for children and 26% for adults. Evaluation of the seizure types for adult and pediatric patients demonstrated that both partial and generalized SE occur with a high frequency in these populations. Based on the incidence of SE actually determined in Richmond, Virginia, we project 126,000 to 195,000 SE events with 22,200 to 42,000 deaths per year in the United States. The majority of SE patients had no history of epilepsy. These results indicate that SE is a common neurologic emergency.read more
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Evidence-Based Guideline: Treatment of Convulsive Status Epilepticus in Children and Adults: Report of the Guideline Committee of the American Epilepsy Society
Tracy A. Glauser,Shlomo Shinnar,David Gloss,Brian K. Alldredge,Ravindra Arya,Jacquelyn L. Bainbridge,Mary A Bare,Thomas P. Bleck,W. Edwin Dodson,Lisa Garrity,Andy Jagoda,Daniel H. Lowenstein,John M. Pellock,James Riviello,Edward P. Sloan,David M. Treiman +15 more
TL;DR: Despite the paucity of well-designed randomized controlled trials, practical conclusions and an integrated treatment algorithm for the treatment of convulsive status epilepticus across the age spectrum (infants through adults) can be constructed.
Journal ArticleDOI
Prevalence of nonconvulsive status epilepticus in comatose patients.
Alan R. Towne,Elizabeth Waterhouse,Jane G. Boggs,L.K. Garnett,A.J. Brown,J.R. Smith,Robert J. DeLorenzo +6 more
TL;DR: This large-scale EEG evaluation of comatose patients without clinical signs of seizure activity found that NCSE is an under-recognized cause of coma, occurring in 8% of all comatoses patients without signs of seizures activity.
Journal ArticleDOI
Refractory Status Epilepticus: Frequency, Risk Factors, and Impact on Outcome
Stephan A. Mayer,Jan Claassen,Johnny Lokin,Felicia A. Mendelsohn,Lyle J. Dennis,Brian-Fred Fitzsimmons +5 more
TL;DR: Refractory status epilepticus occurs in approximately 30% of patients with SE and is associated with increased hospital length of stay and functional disability, and nonconvulsive SE and focal motor seizures at onset are risk factors for RSE.
Journal ArticleDOI
Persistent Nonconvulsive Status Epilepticus After the Control of Convulsive Status Epilepticus
Robert J. DeLorenzo,Elizabeth J. Waterhouse,Alan R. Towne,Jane G. Boggs,Daijin Ko,G. A. DeLorenzo,A.J. Brown,L.K. Garnett +7 more
TL;DR: The present study was initiated to determine whether control of CSE by standard treatment protocols was sufficient to terminate electrographic seizures.
References
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Journal ArticleDOI
Determinants of Mortality in Status Epilepticus
TL;DR: These findings represent the first multivariate analysis of predictive indicators of mortality in SE and demonstrate that specific factors influence mortality rate in SE.
The treatment of convulsive status epilepticus, recommendations of the epilepsy foundation of america’s working group on status epilepticus
TL;DR: Common to all patients is the need for a clear plan, prompt administration of appropriate drugs in adequate doses, and attention to the possibility of apnea, hypoventilation, or other metabolic abnormalities.
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Status epilepticus: Causes, clinical features and consequences in 98 patients
TL;DR: The etiology, clinical features and outcome of generalized major motor status epilepticus in 98 patients over the age of 14 years have been reviewed and it was found that a poor outcome of the status was more likely as its duration increased, and the morbidity rate was 12.5 percent among patients.
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Low morbidity and mortality of status epilepticus in children
TL;DR: The mortality and incidence of sequelae following status epilepticus was low and primarily a function of etiology, and age did not affect outcome within each cause.
Journal ArticleDOI
Status epilepticus at an urban public hospital in the 1980s
TL;DR: The clinical course of adult patients treated for generalized status epilepticus at the San Francisco General Hospital from 1980 to 1989 is reviewed to determine whether the etiologies of SE have changed over the last two decades, and to investigate the relationships between etiology, response to anticonvulsant therapy, and short-term clinical outcome.