Journal ArticleDOI
A retrospective study of poisoning in Tehran.
Reads0
Chats0
TLDR
The majority of poisoning cases in adults occur intentionally and in children accidentally, and in adults and children accidentally.Abstract:
Objective: To examine the causes and majority of poisoning in Tehran. Methods: The 7000 poisoning cases referred to Loghman-Hakim Hospital in Tehran over six months in 1994 were evaluated retrospectively. Results: The overall female to male ratio was 1.8:1. Most poisoning occurred in the age range 2-6 y for children and 21-40 y for adults. Oral ingestion was the most common route of intoxication. In children, boys had a higher frequency of poisoning than girls. Most cases of children were referred to the hospital between 8 am and 8 pm. In adults referred to the hospital, there was little diurnal variation in poisoning presentations. In adults, drugs were the most common cause of intoxication (60.2%). Of these, benzodiazepines (24.5%) were the most frequent, followed by antidepressants (20.5%) and analgesics (18%). Pesticide and opiate intoxications were also commonly observed. In children, after drugs (32.1%), hydrocarbons were the most frequent cause of poisoning (19.2%). Pesticide poisonings wer...read more
Citations
More filters
Journal Article
Pesticides and oxidative stress: a review.
TL;DR: It is concluded that stimulation of free radical production, induction of lipid peroxidation, and disturbance of the total antioxidant capability of the body are mechanisms of toxicity in most pesticides, including organophosphates, bipyridyl herbicides and organochlorines.
Journal ArticleDOI
The global distribution of fatal pesticide self-poisoning: systematic review
TL;DR: Pesticide self-poisoning accounts for about one-third of the world's suicides, and epidemiological and toxicological data suggest that many of these deaths might be prevented if the use of pesticides most toxic to humans was restricted, pesticides could be safely stored in rural communities, and the accessibility and quality of care for poisoning could be improved.
Journal ArticleDOI
Patterns and problems of deliberate self‐poisoning in the developing world
TL;DR: It is emphasized the importance of determining whether interventions aimed at reducing poison absorption actually produce a clinical benefit, reducing death and complication rates, to rapidly reduce the number of deaths from self-poisoning in the developing world.
Journal ArticleDOI
Toxic influence of organophosphate, carbamate, and organochlorine pesticides on cellular metabolism of lipids, proteins, and carbohydrates: a systematic review.
TL;DR: In this article, the authors conducted a systematic search for the years 1963-2010 and resulted in 1652 articles and identified that organophosphate (OP), organochlorine (OC), and carbamate (CB) compounds are widely used in agricultural and indoor purposes and that OP and OC impair the enzymatic pathways involved in metabolism of carbohydrates, fats and protein within cytoplasm, mitochondria, and proxisomes.
Journal ArticleDOI
Oxidative stress and cholinesterase inhibition in saliva and plasma of rats following subchronic exposure to malathion
TL;DR: It is concluded that in OP subchronic exposure, depression of ChE is accompanied by induction of oxidative stress that might be beneficial in monitoring OP toxicity.
References
More filters
Journal ArticleDOI
Antidepressants, depression and suicide: an analysis of the San Diego study☆
TL;DR: The data suggest that more suicides might be averted by decisively treating Depressed patients with ADs, including strict monitoring of dosage and compliance, than by not treating them to avoid AD overdoses.
Journal ArticleDOI
Suicide and other causes of death in a five-year follow-up of patients treated for self-poisoning in Oslo.
TL;DR: Logistic regression analysis demonstrated that male sex, age above 50 years and the lowest social group were factors on admission associated with death in the follow‐up period and self‐destructiveness and slow suicide in substance abuse were associated with subsequent suicide.
Journal Article
Underreporting of fatal cases to a regional poison control center.
TL;DR: Most fatal cases of poisoning and drug overdose are not detected through poison control center surveillance, and health planners and policy makers should recognize the implications of case underreporting.
Journal ArticleDOI
Tricyclic antidepressant overdose: Emergency department findings as predictors of clinical course
TL;DR: The authors found that major manifestations of toxicity on ED evaluation (altered mental status, seizures, arrhythmias, and conduction defects) were commonly associated with a complicated hospital course and support the concept that proper ED evaluation can identify a large body of patients with trivial ingestions who may not require hospital observation.
Journal ArticleDOI
Attempted suicide by poisoning in the Sofia region.
TL;DR: Data on 9235 persons who had attempted suicide and been admitted to hospital over an eight-year period showed that a female:male ratio of 4:1 in young subjects gradually decreased with age; from the age of 79, the number of men slightly exceeded the numberof women.