Journal ArticleDOI
A review of health related quality of life in systemic lupus erythematosus
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TLDR
Health-related quality of life (HRQoL) is reduced in SLE patients; HRZoL is not correlated to disease activity or damage; age appears to have a negative impact on HRQeL especially physical health but the effect of disease duration is unclear.Citations
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Psychosocial Aspects of Chronic Disease: ESRD as a Paradigmatic Illness
TL;DR: Ch Chronically ill ESRD patients who undergo treatment with constant interaction and observation by medical staff are potentially an ideal group for evaluation of the effects of stress and psychosocial factors on outcomes in those with chronic disease, as an excellent patient population for intervention to reduce morbidity and mortality.
Journal ArticleDOI
Prevalence and burden of pediatric-onset systemic lupus erythematosus.
TL;DR: Pediatric-onset SLE (pSLE) represents 10–20% of all SLE cases, and is associated with higher disease severity, including more-rapid damage accrual, than adult-onsets SLE.
Journal ArticleDOI
Biological mechanisms of chronic fatigue
TL;DR: In this paper, the authors provide an overview of fatigue in chronic autoimmune and inflammatory disease. But, they do not consider the role of specific genes in chronic fatigue in the development of these diseases.
Journal ArticleDOI
Quality of life in cutaneous lupus erythematosus.
Rachel G. Klein,Rachel G. Klein,Siamak Moghadam-Kia,Siamak Moghadam-Kia,Lynne Taylor,Christopher M. Coley,Joyce Okawa,Joyce Okawa,Jonathan LoMonico,Jonathan LoMonico,Mary-Margaret Chren,Victoria P. Werth,Victoria P. Werth +12 more
TL;DR: Patients with cutaneous lupus have very impaired quality of life, particularly from an emotional perspective, and factors related to poorquality of life include female gender, generalized disease, severe disease, distribution of lesions, and younger age.
Journal ArticleDOI
Quality of life over time in patients with systemic lupus erythematosus
TL;DR: The SF-36 in SLE patients with established disease changed little over an 8-year period and changes in theSF-36 were not affected by disease activity, steroids, or damage accumulation during the interval, but were affected by the presence of fibromyalgia.
References
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Journal ArticleDOI
The MOS 36-Item Short-Form Health Survey (SF-36): II. Psychometric and clinical tests of validity in measuring physical and mental health constructs.
TL;DR: In this article, cross-sectional data from the Medical Outcomes Study (MOS) were analyzed to test the validity of the MOS 36-Item Short-Form Health Survey (SF-36) scales as measures of physical and mental health constructs.
Journal ArticleDOI
Derivation of the SLEDAI. A disease activity index for lupus patients. The Committee on Prognosis Studies in SLE.
TL;DR: The development of the SLEDAI is described, a validated model of experienced clinicians' global assessments of disease activity in lupus, which represents the consensus of a group of experts in the field of l upus research.
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Reliability and validity of six systems for the clinical assessment of disease activity in systemic lupus erythematosus
TL;DR: Six systems for defining and evaluating disease activity in patients with systemic lupus erythematosus (SLE) were tested and the BILAG, SLE-DAI, and SLAM systems appear to have better psychometric properties than the others for clinical research.
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The reliability of the Systemic Lupus International Collaborating Clinics/American College of Rheumatology Damage Index in patients with systemic lupus erythematosus.
Dafna D. Gladman,Murray B. Urowitz,Charles H. Goldsmith,Paul R. Fortin,Ellen M. Ginzler,Caroline Gordon,John G. Hanly,David A. Isenberg,Kenneth C. Kalunian,Ola Nived,Michelle Petri,Jorge Sánchez-Guerrero,M L Snaith,Gunnar Sturfelt +13 more
TL;DR: Physicians from different centers are able to assess patients with SLE in a reproducible way, using the SLEDAI to assess disease activity and the SLICC/ACR Damage Index to assess accumulated damage.
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The BILAG index: a reliable and valid instrument for measuring clinical disease activity in systemic lupus erythematosus.
Elaine M Hay,P.A. Bacon,Caroline Gordon,David A. Isenberg,P. Maddison,Michael L Snaith,Deborah P M Symmons,N. Viner,A. S. Zoma +8 more
TL;DR: The BILAG index had good overall sensitivity and specificity when compared with the 'gold standard' criterion (starting or increasing disease-modifying therapy), and for each organ-based system, with the exception of the neurological system.