A revised structure for fucoidan may explain some of its biological activities
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TLDR
The revised average structure for fucoidan is consistent with previous studies suggesting a branched random coil as the best model for this polysaccharide and the proposed model is a closer structural analogue of the sulfated carbohydrate ligands that bind to selectins.About:
This article is published in Journal of Biological Chemistry.The article was published on 1993-10-15 and is currently open access. It has received 485 citations till now. The article focuses on the topics: Fucose & Fucoidan.read more
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Fucoidan: Structure and Bioactivity
TL;DR: This review summarizes the research progress on the structure and bioactivity of fucoidan and the relationships between structure andBioactivity and several fucoidans’ structures have been solved.
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Chemical Structures and Bioactivities of Sulfated Polysaccharides from Marine Algae
TL;DR: The present paper will provide an update on the structural chemistry of the major sulfated polysaccharides synthesized by seaweeds including the galactans, ulvans, and fucans and the recent findings on the anticoagulant/antithrombotic, antiviral, immuno-inflammatory, antilipidemic and antioxidant activities of sulfated Polysaccharide and their potential for therapeutic application.
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Biological activities and potential health benefits of sulfated polysaccharides derived from marine algae
TL;DR: An overview of biological activities and potential health benefits of SPs derived from marine algae, as well as potential products in nutraceutical, pharmaceutical and cosmeceutical areas are presented.
Journal ArticleDOI
Medicinal and pharmaceutical uses of seaweed natural products: A review
TL;DR: The literature was searched for natural products from marine macroalgae in the Rhodophyta, Phaeophyta and Chlorophyta with biological and pharmacological activity and substances that currently receive most attention from pharmaceutical companies for use in drug development, or from researchers in the field of medicine-related research include: sulphated polysaccharides as antiviral substances.
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Sulfated fucans, fresh perspectives : structures, functions, and biological properties of sulfated fucans and an overview of enzymes active toward this class of polysaccharide
Olivier Berteau,Barbara Mulloy +1 more
TL;DR: The availability of purified fucans and fucan fractions with simple, but varied structures, in conjunction with the development of new enzymatic tools, demonstrate that the biological properties of sulfation are not only a simple function of their charge density but also are determined by detailed structural features.
References
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Colorimetric Method for Determination of Sugars and Related Substances
TL;DR: In this article, a method was developed to determine submicro amounts of sugars and related substances using a phenol-sulfuric acid reaction, which is useful for the determination of the composition of polysaccharides and their methyl derivatives.
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A modified uronic acid carbazole reaction
T. Bitter,Helen Muir +1 more
TL;DR: It has been found possible to distinguish betweenHeparin, heparin derivatives, and other polyuronides of connective tissue by comparing the effect of chlorides on the color yield in both procedures by modifying Dische's carbazole reaction for uronic acid in the presence of borate.
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A simple and rapid method for the permethylation of carbohydrates
Ionel Ciucanu,Francisc Kerek +1 more
TL;DR: In this paper, a new method for the permethylation of sugars involving methyl iodide, a solid base (NaOH, KOH, or tert-BuOH/NaOH), and methyl sulphoxide was suggested.
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A simple and rapid preparation of alditol acetates for monosaccharide analysis
TL;DR: In this paper, a simple and rapid method for the preparation of alditol acetates from monosaccharides is described, which can be performed in a single tube without transfers or evaporations.
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Selectins: interpreters of cell-specific carbohydrate information during inflammation.
TL;DR: The biology of these carbohydrate-binding adhesive proteins are reviewed and the potential for developing anti-inflammatory antagonists that could inhibit binding events that are selectin-mediated is discussed.
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