Fucoidan: Structure and Bioactivity
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TLDR
This review summarizes the research progress on the structure and bioactivity of fucoidan and the relationships between structure andBioactivity and several fucoidans’ structures have been solved.Abstract:
Fucoidan refers to a type of polysaccharide which contains substantial percentages of L-fucose and sulfate ester groups, mainly derived from brown seaweed. For the past decade fucoidan has been extensively studied due to its numerous interesting biological activities. Recently the search for new drugs has raised interest in fucoidans. In the past few years, several fucoidans' structures have been solved, and many aspects of their biological activity have been elucidated. This review summarizes the research progress on the structure and bioactivity of fucoidan and the relationships between structure and bioactivity.read more
Citations
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Marine natural products.
TL;DR: This review covers the literature published in 2014 for marine natural products, with 1116 citations referring to compounds isolated from marine microorganisms and phytoplankton, green, brown and red algae, sponges, cnidarians, bryozoans, molluscs, tunicates, echinoderms, mangroves and other intertidal plants and microorganisms.
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TL;DR: This work highlights this rapidly advancing area of algal science with a particular focus on the key research required to assess better the health benefits of an alga or algal product.
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Chemical Structures and Bioactivities of Sulfated Polysaccharides from Marine Algae
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Biological activities and potential health benefits of sulfated polysaccharides derived from marine algae
TL;DR: An overview of biological activities and potential health benefits of SPs derived from marine algae, as well as potential products in nutraceutical, pharmaceutical and cosmeceutical areas are presented.
References
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Journal ArticleDOI
A comparative study of the anti-inflammatory, anticoagulant, antiangiogenic, and antiadhesive activities of nine different fucoidans from brown seaweeds
Albana Cumashi,N. A. Ushakova,M. E. Preobrazhenskaya,Armida D'Incecco,Antonio Piccoli,Licia Totani,Nicola Tinari,Galina E. Morozevich,A. E. Berman,Maria I. Bilan,Anatolii I. Usov,Nadezhda E. Ustyuzhanina,Alexey A. Grachev,Craig J. Sanderson,Maeve Kelly,Gabriel A. Rabinovich,Stefano Iacobelli,Nikolay E. Nifantiev +17 more
TL;DR: The anti-inflammatory, antiangiogenic, anticoagulant, and antiadhesive properties of fucoidans obtained from nine species of brown algae were studied to provide a new rationale for the development of potential drugs for thrombosis, inflammation, and tumor progression.
Journal ArticleDOI
Antioxidant activity of sulfated polysaccharide fractions extracted from Laminaria japonica
TL;DR: Fucoidan, a group of sulfated heteropolysaccharide, was extracted from Laminaria japonica, an important economic alga species in China as mentioned in this paper.
Journal ArticleDOI
A revised structure for fucoidan may explain some of its biological activities
TL;DR: The revised average structure for fucoidan is consistent with previous studies suggesting a branched random coil as the best model for this polysaccharide and the proposed model is a closer structural analogue of the sulfated carbohydrate ligands that bind to selectins.
Journal ArticleDOI
Antioxidant activities of sulfated polysaccharides from brown and red seaweeds
Micheline Cristiane Rocha de Souza,Cybelle Teixeira Marques,Celina Maria P. Guerra Dore,Fernando Roberto Ferreira Silva,Hugo Alexandre Oliveira Rocha,Edda Lisboa Leite +5 more
TL;DR: The results clearly indicate the beneficial effect of algal polysaccharides as antioxidants in the food industry, as iota, kappa and lambda carrageenans had an inhibitory effect on the formation of hydroxyl radicals and fucan fractions showed low antioxidant activity relative to fucoidan.
Journal ArticleDOI
Fucoidans from the brown seaweed Adenocystis utricularis: extraction methods, antiviral activity and structural studies
TL;DR: Fractionation with the cationic detergent cetrimide has allowed achieving a better separation of the galactofucan and uronofucoidan components, which show a high inhibitory activity against herpes simplex virus 1 and 2, with no cytotoxicity.
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A comparative study of the anti-inflammatory, anticoagulant, antiangiogenic, and antiadhesive activities of nine different fucoidans from brown seaweeds
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