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A spelling device for the paralysed

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TLDR
A new means of communication for the completely paralysed that uses slow cortical potentials of the electro-encephalogram to drive an electronic spelling device is developed.
Abstract
When Jean-Dominique Bauby suffered from a cortico-subcortical stroke that led to complete paralysis with totally intact sensory and cognitive functions, he described his experience in The Diving-Bell and the Butterfly1 as “something like a giant invisible diving-bell holds my whole body prisoner”. This horrifying condition also occurs as a consequence of a progressive neurological disease, amyotrophic lateral sclerosis, which involves progressive degeneration of all the motor neurons of the somatic motor system. These ‘locked-in’ patients ultimately become unable to express themselves and to communicate even their most basic wishes or desires, as they can no longer control their muscles to activate communication devices. We have developed a new means of communication for the completely paralysed that uses slow cortical potentials (SCPs) of the electro-encephalogram to drive an electronic spelling device.

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Brain-computer interfaces for communication and control.

TL;DR: With adequate recognition and effective engagement of all issues, BCI systems could eventually provide an important new communication and control option for those with motor disabilities and might also give those without disabilities a supplementary control channel or a control channel useful in special circumstances.
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Neuronal ensemble control of prosthetic devices by a human with tetraplegia

TL;DR: Initial results for a tetraplegic human using a pilot NMP suggest that NMPs based upon intracortical neuronal ensemble spiking activity could provide a valuable new neurotechnology to restore independence for humans with paralysis.
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BCI2000: a general-purpose brain-computer interface (BCI) system

TL;DR: This report is intended to describe to investigators, biomedical engineers, and computer scientists the concepts that the BCI2000 system is based upon and gives examples of successful BCI implementations using this system.
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Brain-computer interfaces for communication and control

TL;DR: The brain's electrical signals enable people without muscle control to physically interact with the world through the use of their brains' electrical signals.
Journal ArticleDOI

Learning to Control a Brain–Machine Interface for Reaching and Grasping by Primates

TL;DR: It is demonstrated that primates can learn to reach and grasp virtual objects by controlling a robot arm through a closed-loop brain–machine interface (BMIc) that uses multiple mathematical models to extract several motor parameters from the electrical activity of frontoparietal neuronal ensembles.
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