Journal ArticleDOI
A stereoselective total synthesis of estrone by an intramolecular cycloaddition reaction of olefinic o-quinodimethane.
About:
This article is published in Journal of the American Chemical Society.The article was published on 1977-05-11. It has received 52 citations till now. The article focuses on the topics: Cycloaddition & Total synthesis.read more
Citations
More filters
Journal ArticleDOI
A Comprehensive History of Arynes in Natural Product Total Synthesis
TL;DR: All reports of total syntheses that utilize arynes in ways that build complexity or introduce motifs essential to the completion of their targets are recounted.
Journal ArticleDOI
o-Quinodimethanes: Efficient Intermediates in Organic Synthesis.
José L. Segura,Nazario Martín +1 more
Journal ArticleDOI
Recent advances in the application of Diels-Alder reactions involving o-quinodimethanes, aza-o-quinone methides and o-quinone methides in natural product total synthesis.
Baochao Yang,Shuanhu Gao +1 more
TL;DR: This review summarizes recent advances in Diels-Alder reactions involving in situ-generated o-QDMs, o- QMs and aza-o-QMs, highlighting the power and potential of this strategy in organic synthesis and natural product total synthesis.
Journal ArticleDOI
Aryne-based strategy in the total synthesis of naturally occurring polycyclic compounds.
TL;DR: The total syntheses of polycyclic natural products by exploiting an aryne as the key reactive species are reviewed and early examples and recent reports on the use of arynes in multistep syntheses are described.
Journal ArticleDOI
Cyclobutarenes and Related Compounds
Related Papers (5)
Intramolecular Cycloaddition Reactions of ortho-Quinodimethanes in Organic Synthesis
Recent advances in the total synthesis of steroids via intramolecular cycloaddition reactions
Tetsuji Kametani,Hideo Nemoto +1 more