Journal ArticleDOI
A study of polyuridylic acid.
J.C. Thrierr,M. Dourlent,M. Leng +2 more
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TLDR
The results indicate that at low temperature, polyuridylic acid adopts a double-helical structure resulting from the folding of the molecule on itself (a single hairpin), and upon heating, branching takes place leading to the formation of multi-hairpins.About:
This article is published in Journal of Molecular Biology.The article was published on 1971-06-28. It has received 73 citations till now. The article focuses on the topics: Circular dichroism.read more
Citations
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RNA-Based Coacervates as a Model for Membraneless Organelles: Formation, Properties, and Interfacial Liposome Assembly.
TL;DR: It is shown that complex coacervates composed of low complexity RNA (polyuridylic acid, polyU) and short polyamines (spermine and spermidine) share many features of IDP-based coacers, and that lipid vesicles assemble at the droplet interface without impeding RNA entry/egress.
Journal ArticleDOI
RNA force field with accuracy comparable to state-of-the-art protein force fields
TL;DR: An extensive revision of a widely used RNA force field is introduced in which the parameters have been modified, based on quantum mechanical calculations and existing experimental information, to more accurately reflect the fundamental forces that stabilize RNA structures.
Journal ArticleDOI
Two-quantum UV photochemistry of nucleic acids: comparison with conventional low-intensity UV photochemistry and radiation chemistry.
TL;DR: The action of high-intensity laser u.v. radiation on nucleic acid molecules and their constituents in vitro and in vivo is compared with the results of low-intensity u.V. photolysis and gamma-radiolysis.
Journal ArticleDOI
Formaldehyde as a probe of DNA structure. 3. Equilibrium denaturation of DNA and synthetic polynucleotides.
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A quantitative analysis of proflavine binding to polyadenylic acid, polyuridylic acid, and transfer RNA.
Maurice Dourlent,Claude Hélène +1 more
TL;DR: It is proposed that the mode of interaction between proflavine and all classes of polynucleotides (DNA, RNA, synthetic polymers) is similar in nature.
References
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Book
The nucleic acids
Erwin. Chargaff,J. N. Davidson +1 more
TL;DR: Nucleic Acid is a complex biomolecule that stores genetic information in the form of a code that is necessary for life.
Journal ArticleDOI
The physical and chemical properties of nucleic acids.
G Felsenfeld,H T Miles +1 more
Journal ArticleDOI
Helix-random coil transitions in synthetic DNAs of alternating sequence
R.B. Inman,Robert L. Baldwin +1 more
TL;DR: The helix-coil transitions of two synthetic DNA copolymers have been studied as models for the behavior of natural DNAs and in order to learn how to form hybrid molecules by a coil-helix transition.
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Studies of the temperature-dependent conformation and phase separation of polyriboadenylic acid solutions at neutral pH
Henryk Eisenberg,Gary Felsenfeld +1 more
TL;DR: The results show that poly A forms a highly extended structure at low temperature but that this structure is rapidly disrupted as the fraction of bases in stacks falls below unity, consistent with the existence of a structure formed by a non-co-operative process.
Journal ArticleDOI
Conformation of polyribouridylic acid in solution
L.Daniel Inners,Gary Felsenfeld +1 more
TL;DR: The unperturbed dimensions of the poly rU molecule do not vary greatly with temperature, as expected for a polynucleotide with little or no base stacking, and the characteristic ratio 2 > nl 2 is 17.6, corresponding to a quite highly extended random coil.