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Journal ArticleDOI

A successful eradication campaign. Global eradication of smallpox.

Frank Fenner
- 01 Sep 1982 - 
- Vol. 4, Iss: 5, pp 916-930
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TLDR
Some of the problems associated with the eradication of smallpox in two countries where eradication was difficult, India and Ethiopia, are highlighted and the measures adopted to overcome the problems are highlighted.
Abstract
Smallpox was the first important disease to be eradicated; it was the success of the Smallpox Eradication Programme that inspired this conference. Several biological reasons favored the eradication of smallpox, the most important of which were probably that recurrent infectivity did not occur, that there was no animal reservoir, and that an effective stable vaccine was available. The importance of smallpox as a disease that travelers might import into countries free of smallpox provided a powerful stimulus for its global eradication. This paper highlights some of the problems associated with the eradication of smallpox in two countries where eradication was difficult, India and Ethiopia, and the measures adopted to overcome the problems. The paper also stresses the importance of the development of methods for the certification of smallpox eradication from countries, from regions, and finally from the whole world. It is noted that close links between field work and research were important throughout the eradication campaign.

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Citations
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Epidermal immunization by a needle-free powder delivery technology: immunogenicity of influenza vaccine and protection in mice.

TL;DR: Epidermal immunization by a needle-free powder delivery technology: Immunogenicity of influenza vaccine and protection in mice and in mice is studied.
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Variola virus immune evasion design: Expression of a highly efficient inhibitor of human complement

TL;DR: The molecularly engineered and characterized the smallpox inhibitor of complement enzymes (SPICE), a homologue of a vaccinia virulence factor, vaccinia virus complement control protein (VCP), provides the first evidence that variola proteins are particularly adept at overcoming human immunity.
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The smallpox story: life and death of an old disease.

TL;DR: This book discusses the history and present situation of vaccination in Britain, as well as some of the aspects of its use today.
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The architecture and effect of participation: a systematic review of community participation for communicable disease control and elimination. Implications for malaria elimination

TL;DR: The findings of an atypical systematic review of 60 years of literature are reported to arrive at a more comprehensive awareness of the constructs of participation for communicable disease control and elimination and provide guidance for the current malaria elimination campaign.
Book ChapterDOI

Prevention and Control

Thomas Butler
TL;DR: Although plague is relatively well controlled today, being restricted in human cases to less than 1000 per year in all countries except Vietnam and Burma, the disease has the potential for rapid expansion from the endemic foci that exist in many countries.
References
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Journal ArticleDOI

Comparison of white pock (h) mutants of monkeypox virus with parental monkeypox and with variola-like viruses isolated from animals

TL;DR: None of the monkeypox mutants arising spontaneously or after serial, high multiplicity passage resembles ‘whitepox’ viruses in genome structure although near-terminal deletions or symmetrical, terminal rearrangements, relative to parental monkeypox, occurred.
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