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Journal ArticleDOI

Abnormal magnetic-resonance scans of the lumbar spine in asymptomatic subjects. A prospective investigation

TLDR
In this paper, the authors performed magnetic resonance imaging on sixty-seven individuals who had never had low-back pain, sciatica, or neurogenic claudication, and found that about one-third of the subjects were found to have a substantial abnormality.
Abstract
We performed magnetic resonance imaging on sixty-seven individuals who had never had low-back pain, sciatica, or neurogenic claudication. The scans were interpreted independently by three neuro-radiologists who had no knowledge about the presence or absence of clinical symptoms in the subjects. About one-third of the subjects were found to have a substantial abnormality. Of those who were less than sixty years old, 20 per cent had a herniated nucleus pulposus and one had spinal stenosis. In the group that was sixty years old or older, the findings were abnormal on about 57 per cent of the scans: 36 per cent of the subjects had a herniated nucleus pulposus and 21 per cent had spinal stenosis. There was degeneration or bulging of a disc at at least one lumbar level in 35 per cent of the subjects between twenty and thirty-nine years old and in all but one of the sixty to eighty-year-old subjects. In view of these findings in asymptomatic subjects, we concluded that abnormalities on magnetic resonance images must be strictly correlated with age and any clinical signs and symptoms before operative treatment is contemplated.

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Citations
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Cervical myelopathy. current diagnostic and treatment strategies.

TL;DR: Current literature suggests that operative management reliably arrests the progression of myelopathy and may lead to functional improvement in a majority of patients, and surgical procedures must be carefully individualized based on specific clinical and radiographic factors.
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Mechanisms of low back pain: a guide for diagnosis and therapy

TL;DR: This article aims to offer to the clinicians a simple guidance to identify pain generators in a safer and faster way, relying a correct diagnosis and further therapeutical approach.
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Neural blockade for diagnosis and prognosis. A review.

TL;DR: The confusion and complexity that typifies diagnosis in chronic pain may justify the selective use of diagnostic blocks that make anatomic and physiologic sense, even if their validity is incompletely proved.
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Reliability of Physical Examination Items Used for Classification of Patients With Low Back Pain

TL;DR: Reliability of physical examination items used for classification of patients with low back pain suggests that experienced therapist who had trained together were able to agree on the results of examinations and obtain an acceptable level of reliability.
Journal ArticleDOI

Cell transplantation in lumbar spine disc degeneration disease

TL;DR: This study demonstrated that disc cells remained viable after transplantation; transplanted disc cells produced an extracellular matrix that contained components similar to normal intervertebral disc tissue; and provided evidence that cells harvested from adipose tissue might offer a reliable source of regenerative potential capable of bio-restitution.
References
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Journal ArticleDOI

Back pain and sciatica.

TL;DR: Low back pain is usually a self-limiting symptom, but it costs at least $16 billion each year and disables 5.4 million Americans, and the fact that a benign physical condition has such an importa...
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A study of computer-assisted tomography. I. The incidence of positive CAT scans in an asymptomatic group of patients.

TL;DR: To study the type and number of CAT scan abnormalities of the lumbar spine that occur in asymptomatic people, 52 studies from a control population with no history of back trouble were mixed randomly with six scans from patients with surgically proven spinal disease, and all were interpreted by three neuroradiologists in a blinded fashion.
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Abnormal myelograms in asymptomatic patients.

TL;DR: The incidence of myelographic abnormalities in 300 patients who were studied by posterior fossa myelography to establish a diagnosis of acoustic tumor is reported, even though patients had no symptoms of cervical or lumbar nerve root compression at the time of the examination.
Journal ArticleDOI

The question of lumbar discography.

TL;DR: It has not been established whether internal derangement of the lumbar disc is sufficiently symptom-producing to be a therapeutic objective, especially a surgical one, or whether it represetits anything more than an aging process, and the patterns of degeneration seen in 628 of 2,187 discs injected by the Cleveland group and 773 of 6,784 discs injections by Feinberg or 322 of 870 disc injected by Massie and Stevens may represent nothing more than normal patterns for the age
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Lumbar herniated disk disease and canal stenosis: prospective evaluation by surface coil MR, CT, and myelography

TL;DR: The results of this study indicate that a technically adequate MR examination was equivalent to CT and myelography in the diagnosis of lumbar canal stenosis and herniated disk disease.
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