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Journal ArticleDOI

Abnormal magnetic-resonance scans of the lumbar spine in asymptomatic subjects. A prospective investigation

TLDR
In this paper, the authors performed magnetic resonance imaging on sixty-seven individuals who had never had low-back pain, sciatica, or neurogenic claudication, and found that about one-third of the subjects were found to have a substantial abnormality.
Abstract
We performed magnetic resonance imaging on sixty-seven individuals who had never had low-back pain, sciatica, or neurogenic claudication. The scans were interpreted independently by three neuro-radiologists who had no knowledge about the presence or absence of clinical symptoms in the subjects. About one-third of the subjects were found to have a substantial abnormality. Of those who were less than sixty years old, 20 per cent had a herniated nucleus pulposus and one had spinal stenosis. In the group that was sixty years old or older, the findings were abnormal on about 57 per cent of the scans: 36 per cent of the subjects had a herniated nucleus pulposus and 21 per cent had spinal stenosis. There was degeneration or bulging of a disc at at least one lumbar level in 35 per cent of the subjects between twenty and thirty-nine years old and in all but one of the sixty to eighty-year-old subjects. In view of these findings in asymptomatic subjects, we concluded that abnormalities on magnetic resonance images must be strictly correlated with age and any clinical signs and symptoms before operative treatment is contemplated.

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Citations
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Journal ArticleDOI

Lumbar Disc Nomenclature: Version 2.0: Recommendations of the Combined Task Forces of the North American Spine Society, the American Society of Spine Radiology and the American Society of Neuroradiology

TL;DR: A document that, since 2001, has provided a widely acceptable nomenclature that helps maintain consistency and accuracy in the description of the anatomic and physiologic properties of the normal and abnormal lumbar disc is revised and updated.
Journal ArticleDOI

Rapid magnetic resonance imaging vs radiographs for patients with low back pain: a randomized controlled trial.

TL;DR: Rapid MRIs and radiographs resulted in nearly identical outcomes for primary care patients with low back pain, and substituting rapid MRI for radiographic evaluations in the primary care setting may offer little additional benefit to patients and it may increase the costs of care because of the increased number of spine operations that patients are likely to undergo.
Journal ArticleDOI

Cervical Spondylotic Myelopathy The Clinical Phenomenon and the Current Pathobiology of an Increasingly Prevalent and Devastating Disorder

TL;DR: The natural history of CSM, epidemiology, clinical presentation, and current methods of clinical management are reported, along with the current state of basic scientific research in the field.

Results of the Bone and Joint Decade 2000–2010 Task Force on Neck Pain and Its Associated Disorders

TL;DR: Psychosocial factors, including psychologic health, coping patterns, and need to socialize, were the strongest prognostic factors in neck pain and its associated disorders.
Journal ArticleDOI

Stem cell therapy for intervertebral disc regeneration: obstacles and solutions

TL;DR: Detailed basic research on IVD cells and their niche indicates that transplanted cells are unable to survive and adapt in the avascular niche of the IVD, and therefore this therapeutic strategy to succeed needs to be better defined.
References
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Journal ArticleDOI

Back pain and sciatica.

TL;DR: Low back pain is usually a self-limiting symptom, but it costs at least $16 billion each year and disables 5.4 million Americans, and the fact that a benign physical condition has such an importa...
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A study of computer-assisted tomography. I. The incidence of positive CAT scans in an asymptomatic group of patients.

TL;DR: To study the type and number of CAT scan abnormalities of the lumbar spine that occur in asymptomatic people, 52 studies from a control population with no history of back trouble were mixed randomly with six scans from patients with surgically proven spinal disease, and all were interpreted by three neuroradiologists in a blinded fashion.
Journal ArticleDOI

Abnormal myelograms in asymptomatic patients.

TL;DR: The incidence of myelographic abnormalities in 300 patients who were studied by posterior fossa myelography to establish a diagnosis of acoustic tumor is reported, even though patients had no symptoms of cervical or lumbar nerve root compression at the time of the examination.
Journal ArticleDOI

The question of lumbar discography.

TL;DR: It has not been established whether internal derangement of the lumbar disc is sufficiently symptom-producing to be a therapeutic objective, especially a surgical one, or whether it represetits anything more than an aging process, and the patterns of degeneration seen in 628 of 2,187 discs injected by the Cleveland group and 773 of 6,784 discs injections by Feinberg or 322 of 870 disc injected by Massie and Stevens may represent nothing more than normal patterns for the age
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Lumbar herniated disk disease and canal stenosis: prospective evaluation by surface coil MR, CT, and myelography

TL;DR: The results of this study indicate that a technically adequate MR examination was equivalent to CT and myelography in the diagnosis of lumbar canal stenosis and herniated disk disease.
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