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Journal ArticleDOI

Abnormal magnetic-resonance scans of the lumbar spine in asymptomatic subjects. A prospective investigation

TLDR
In this paper, the authors performed magnetic resonance imaging on sixty-seven individuals who had never had low-back pain, sciatica, or neurogenic claudication, and found that about one-third of the subjects were found to have a substantial abnormality.
Abstract
We performed magnetic resonance imaging on sixty-seven individuals who had never had low-back pain, sciatica, or neurogenic claudication. The scans were interpreted independently by three neuro-radiologists who had no knowledge about the presence or absence of clinical symptoms in the subjects. About one-third of the subjects were found to have a substantial abnormality. Of those who were less than sixty years old, 20 per cent had a herniated nucleus pulposus and one had spinal stenosis. In the group that was sixty years old or older, the findings were abnormal on about 57 per cent of the scans: 36 per cent of the subjects had a herniated nucleus pulposus and 21 per cent had spinal stenosis. There was degeneration or bulging of a disc at at least one lumbar level in 35 per cent of the subjects between twenty and thirty-nine years old and in all but one of the sixty to eighty-year-old subjects. In view of these findings in asymptomatic subjects, we concluded that abnormalities on magnetic resonance images must be strictly correlated with age and any clinical signs and symptoms before operative treatment is contemplated.

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Electrophysiology of radiculopathies

TL;DR: The anatomy, pathophysiology, and clinical evaluation of radiculopathies are discussed, and evidence based on large series of patients that somatosensory evoked potentials can be helpful for evaluating patients with multilevel injury, patients where electrophysiological studies may have their greatest clinical utility.
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A potential role for cell-based therapeutics in the treatment of intervertebral disc herniation.

TL;DR: Early results, although preliminary, support the premise as a positive approach to repopulate the anatomy with autologous disc chondrocytes – cells capable of restoring the matrix and retaining the mechanical balance by which the disc functions.
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A Critical Appraisal of the Evidence for Selective Nerve Root Injection in the Treatment of Lumbosacral Radiculopathy

TL;DR: A review of the evidence for TFESIs found level III (moderate) evidence in support of these minimally invasive and safe procedures in treating painful radicular symptoms, but conclusive evidence (level I) is lacking.
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Occult Lumbar Lateral Spinal Stenosis in Neural Foramina Subjected to Physiologic Loading

TL;DR: Flexion, extension, lateral bending, and axial rotation significantly changed the anatomic relationships of the ligamentum flavum and intervertebral disk to the spinal nerve roots.
Journal ArticleDOI

MSU classification for herniated lumbar discs on MRI: toward developing objective criteria for surgical selection.

TL;DR: The prospective clinical outcome study of 200 cases with 5-year follow-up was used to develop and validate an MRI-based classification scheme that can provide objective criteria for surgery that may lead to a higher percentage of good to excellent outcomes.
References
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Journal ArticleDOI

Back pain and sciatica.

TL;DR: Low back pain is usually a self-limiting symptom, but it costs at least $16 billion each year and disables 5.4 million Americans, and the fact that a benign physical condition has such an importa...
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A study of computer-assisted tomography. I. The incidence of positive CAT scans in an asymptomatic group of patients.

TL;DR: To study the type and number of CAT scan abnormalities of the lumbar spine that occur in asymptomatic people, 52 studies from a control population with no history of back trouble were mixed randomly with six scans from patients with surgically proven spinal disease, and all were interpreted by three neuroradiologists in a blinded fashion.
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Abnormal myelograms in asymptomatic patients.

TL;DR: The incidence of myelographic abnormalities in 300 patients who were studied by posterior fossa myelography to establish a diagnosis of acoustic tumor is reported, even though patients had no symptoms of cervical or lumbar nerve root compression at the time of the examination.
Journal ArticleDOI

The question of lumbar discography.

TL;DR: It has not been established whether internal derangement of the lumbar disc is sufficiently symptom-producing to be a therapeutic objective, especially a surgical one, or whether it represetits anything more than an aging process, and the patterns of degeneration seen in 628 of 2,187 discs injected by the Cleveland group and 773 of 6,784 discs injections by Feinberg or 322 of 870 disc injected by Massie and Stevens may represent nothing more than normal patterns for the age
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Lumbar herniated disk disease and canal stenosis: prospective evaluation by surface coil MR, CT, and myelography

TL;DR: The results of this study indicate that a technically adequate MR examination was equivalent to CT and myelography in the diagnosis of lumbar canal stenosis and herniated disk disease.
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