Journal ArticleDOI
Adipocyte and adipogenesis
TLDR
Adipogenesis is the process during which fibroblast like preadipocytes developed into mature adipocytes, a well-orchestrated multistep process that requires the sequential activation of numerous transcription factors, including the CCAAT/enhancer-binding protein (C/EBP) gene family and peroxisome proliferator activated receptor-γ (PPAR-γ).About:
This article is published in European Journal of Cell Biology.The article was published on 2013-06-01. It has received 444 citations till now. The article focuses on the topics: Adipogenesis & Adipose tissue.read more
Citations
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Journal ArticleDOI
Adipose tissue in control of metabolism
Liping Luo,Meilian Liu +1 more
TL;DR: This review will summarize the recent findings of adipose tissue in the control of metabolism, focusing on its endocrine and thermogenic function.
Journal ArticleDOI
Obesity and cancer: the role of adipose tissue and adipo-cytokines-induced chronic inflammation
TL;DR: It is supported that inflammatory state specific of obesity may be important in obesity-cancer link and Dysfunctional adipose tissue in obesity releases a disturbed profile of adipokines with elevated levels of pro-inflammatory factors and a consequent alteration of key signaling mediators.
Journal ArticleDOI
Acute effects of active breaks during prolonged sitting on subcutaneous adipose tissue gene expression: an ancillary analysis of a randomised controlled trial.
Megan S. Grace,Melissa F. Formosa,Kiymet Bozaoglu,Kiymet Bozaoglu,Audrey Bergouignan,Audrey Bergouignan,Audrey Bergouignan,Marta Brozynska,Marta Brozynska,Andrew L. Carey,Camilla Bertuzzo Veiga,Parneet Sethi,Francis Dillon,David A. Bertovic,Michael Inouye,Michael Inouye,Neville Owen,Neville Owen,David W. Dunstan,David W. Dunstan,Bronwyn A. Kingwell +20 more
TL;DR: Preliminary insight is provided into the adipose tissue regulatory systems that may contribute to the physiological effects of interrupting prolonged sitting and how these systems are regulated through regulation of skeletal muscle gene and protein expression and modulation of adipocyte cell cycle.
Journal ArticleDOI
Role of microRNAs in obesity and obesity-related diseases
Giuseppe Iacomino,Alfonso Siani +1 more
TL;DR: The status of current research on the role of miRNAs in obesity and related metabolic abnormalities is summarized and discussed.
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Metabolic syndrome and obesity among users of second generation antipsychotics: A global challenge for modern psychopharmacology.
Leonel E. Rojo,Pablo A. Gaspar,Hernán Silva,L. Risco,Pamela Arena,Karen Cubillos-Robles,Belen Jara +6 more
TL;DR: The scientific bases of SGAs metabolic side effects are not yet elucidated, but the evidence shows that the activation of transcriptional factor SRBP1c, the D1/D2 dopamine, GABA2 and 5HT neurotransmitions are implicated in the SGAs cardiovascular toxicity.
References
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Book
Molecular Cell Biology
TL;DR: Molecular cell biology, Molecular cell biology , مرکز فناوری اطلاعات و اصاع رسانی, کδاوρزی
Journal ArticleDOI
Human Adipose Tissue Is a Source of Multipotent Stem Cells
Patricia A. Zuk,Min Zhu,Peter Ashjian,Daniel A. De Ugarte,Jerry I. Huang,Hiroshi Mizuno,Zeni Alfonso,John K. Fraser,Prosper Benhaim,Marc H. Hedrick +9 more
TL;DR: To confirm whether adipose tissue contains stem cells, the PLA population and multiple clonal isolates were analyzed using several molecular and biochemical approaches and PLA cells exhibited unique characteristics distinct from those seen in MSCs, including differences in CD marker profile and gene expression.
Journal ArticleDOI
Adipose Tissue as an Endocrine Organ
Erin E. Kershaw,Jeffrey S. Flier +1 more
TL;DR: An overview of the endocrine functions of adipose tissue can be found in this paper, where the authors highlight the adverse metabolic consequences of both adipose excess and deficiency, and propose a more rational therapy for these increasingly prevalent disorders.
Journal ArticleDOI
Adipocyte differentiation from the inside out.
TL;DR: Interest in adipogenesis has increased markedly over the past few years with emphasis on the intersection between extracellular signals and the transcriptional cascade that regulates adipocyte differentiation.
Journal ArticleDOI
Understanding Adipocyte Differentiation
TL;DR: Characterization of regulatory regions of adipose-specific genes has led to the identification of the transcription factors peroxisome proliferator-activated receptor-gamma and CCAAT/enhancer binding protein (C/EBP), which play a key role in the complex transcriptional cascade during adipocyte differentiation.