Open AccessJournal Article
Alkaloid studies. 48. The structure of apparicine, a novel Aspidosperma alkaloid.
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This article is published in Journal of The Chemical Society-perkin Transactions 1.The article was published on 1965-09-01 and is currently open access. It has received 2 citations till now. The article focuses on the topics: Aspidosperma alkaloid & Apparicine.read more
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Chemical Diversity and Bioactivities of Monoterpene Indole Alkaloids (MIAs) from Six Apocynaceae Genera
Afrah E. Mohammed,Zainab H. Abdul-Hameed,Modhi O. Alotaibi,Nahed O. Bawakid,Tariq R. Sobahi,Ahmed Abdel-Lateff,Walied M. Alarif +6 more
TL;DR: In this paper, a review of Indole Alkaloids from six genera belonging to the family Apocynaceae is presented, and the genera (Alstonia, Rauvolfia, Kopsia, Ervatamia, and Tabernaemontana, and Rhazya) consist of 400 members and represent 20% of the species.
Journal ArticleDOI
Synthesis and stereochemical determination of an antiparasitic pseudo-aminal type monoterpene indole alkaloid
Yoshihiko Noguchi,Tomoyasu Hirose,Aki Ishiyama,Masato Iwatsuki,Kazuhiko Otoguro,Toshiaki Sunazuka,Satoshi Ōmura +6 more
TL;DR: The first total synthesis of 16-hydroxy-16,22-dihydroapparicine was completed, by combining a phosphine-mediated cascade reaction, diastereoselective nucleophilic addition of 2-acylindole or methylketone via a Felkin–Anh transition state, and chirality transferring intramolecular Michael addition.