Journal ArticleDOI
Alterating The Gut Microbiome By Microbiota Transplantation From Depressed Patients Into Germ-Free Mice Results In Depressive-Like Behaviors Through A Pathway Mediated By The Host’s Metabolism
TLDR
It is demonstrated in these experiments that gut microbiota can physiologically induce depression-like behavior in mice and that dysbiosis of the gut microbiome may have a causal role in the development of depressive-like behaviors, in a pathway that is mediated through the host’s metabolism.About:
This article is published in European Neuropsychopharmacology.The article was published on 2017-01-01. It has received 6 citations till now. The article focuses on the topics: Dysbiosis & Gut flora.read more
Citations
More filters
Journal ArticleDOI
Updated review of research on the gut microbiota and their relation to depression in animals and human beings.
TL;DR: The methodological approaches used for microbiota research are introduced and an overview of current research progress on the modulatory function and composition of the gut microbiota in MDD and the therapeutic effect of probiotics is provided using data from human studies as well as animal experiments.
Journal ArticleDOI
Fecal Microbiota Transplantation: A New Therapeutic Attempt from the Gut to the Brain.
Haoming Xu,Hongli Huang,Youlian Zhou,Hailan Zhao,Jing Xu,Diwen Shou,Yan-Di Liu,Yongjian Zhou,Yuqiang Nie +8 more
TL;DR: Fecal microbiota transplantation (FMT) is a biological therapy that entails transferring the gut microbiota from healthy individuals to patients in order to reconstruct the intestinal microflora in the latter as mentioned in this paper.
Journal ArticleDOI
Gut microbiota alteration and modulation in psychiatric disorders: Current evidence on fecal microbiota transplantation.
TL;DR: Fecal microbiota transplantation (FMT) as mentioned in this paper has been used to induce dysbiosis and to study the disease development, or to heal dysbiotic-related mental disorders by altering neurodevelopment, enhancing neurodegeneration, affecting behaviour and mood.
Journal ArticleDOI
A case report looking at the effects of faecal microbiota transplantation in a patient with bipolar disorder
Journal ArticleDOI
A psychobiotic approach to the treatment of depression: A systematic review and meta-analysis
TL;DR: A meta-analysis based on randomized controlled trials was conducted to clarify the effect of psychobiotics on depression in adults as discussed by the authors , which showed that psychobiotic treatment results in a higher depression score reduction compared with the placebo.
Related Papers (5)
Transferring the blues: Depression-associated gut microbiota induces neurobehavioural changes in the rat.
John R. Kelly,Yuliya E. Borre,Ciaran O' Brien,Ciaran O' Brien,Elaine Patterson,Elaine Patterson,Sahar El Aidy,Sahar El Aidy,Jennifer Deane,Paul J. Kennedy,S. Beers,Karen A. Scott,Gerard M. Moloney,Alan E. Hoban,Lucinda V. Scott,Patrick Fitzgerald,Paul Ross,Catherine Stanton,Gerard Clarke,John F. Cryan,Timothy G. Dinan +20 more