Journal ArticleDOI
Ambient Sampling/Ionization Mass Spectrometry: Applications and Current Trends
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This article is published in Analytical Chemistry.The article was published on 2011-05-06. It has received 517 citations till now. The article focuses on the topics: Desorption electrospray ionization & Sampling (statistics).read more
Citations
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Journal ArticleDOI
Mass Spectrometry: Recent Advances in Direct Open Air Surface Sampling/Ionization
TL;DR: This review focuses on laser-Based Hybrid Techniques Coupled to ESI or Plasma Ionization, as well as two-Step Thermal/Mechanical Desorption/ Ablation (Non-Laser) Techniques, which were developed in this review.
Journal ArticleDOI
Mass spectrometry imaging under ambient conditions.
TL;DR: The role of bioinformatics in acquiring and interpreting the chemical and spatial information obtained through MSI, especially in biological applications for tissue diagnostic purposes is described, and the challenges in ambient MSI are discussed.
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Ambient Ionization Mass Spectrometry
TL;DR: This review sorts different ambient ionization techniques into two main subcategories, primarily on the basis of the ionization processes, that are further differentiated in terms of the approach used for sampling.
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Tissue Imaging Using Nanospray Desorption Electrospray Ionization Mass Spectrometry
TL;DR: The first proof-of-principle experiments indicate the potential of nano-DESI for ambient imaging with a spatial resolution of better than 12 μm, which will enable new imaging mass spectrometry applications in clinical diagnostics, drug discovery, molecular biology, and biochemistry.
Journal ArticleDOI
Classifying human brain tumors by lipid imaging with mass spectrometry
Livia S. Eberlin,Isaiah Norton,Allison L. Dill,Alexandra J. Golby,Keith L. Ligon,Sandro Santagata,R. Graham Cooks,Nathalie Y. R. Agar +7 more
TL;DR: Together, the findings offer proof of concept that intraoperative examination and classification of brain tissue by mass spectrometry can provide surgeons, pathologists, and oncologists with critical and previously unavailable information to rapidly guide surgical resections that can improve management of patients with malignant brain tumors.
References
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Journal ArticleDOI
Mass Spectrometry Sampling Under Ambient Conditions with Desorption Electrospray Ionization
TL;DR: The DESI phenomenon was observed both in the case of conductive and insulator surfaces and for compounds ranging from nonpolar small molecules such as lycopene, the alkaloid coniceine, and small drugs, through polar compounds such as peptides and proteins.
Journal ArticleDOI
Dielectric-barrier Discharges: Their History, Discharge Physics, and Industrial Applications
TL;DR: In this article, the authors discuss the history, discharge physics, and plasma chemistry of dielectric-barrier discharges and their applications and discuss the applications of these discharges.
Journal ArticleDOI
Versatile New Ion Source for the Analysis of Materials in Open Air under Ambient Conditions
TL;DR: DART has demonstrated success in sampling hundreds of chemicals, including chemical agents and their signatures, pharmaceutics, metabolites, peptides and oligosaccharides, synthetic organics, organometallics, drugs of abuse, explosives, and toxic industrial chemicals.
Journal ArticleDOI
Ambient Mass Spectrometry
TL;DR: In DESI as discussed by the authors, electrically charged droplets are directed at the ambient object of interest; they release ions from the surface, which are then vacuumed through the air into a conventional mass spectrometer.
PatentDOI
Laser ablation electrospray ionization (LAESI) for atmospheric pressure, in vivo, and imaging mass spectrometry
Akos Vertes,Peter Nemes +1 more
TL;DR: In this paper, a process and apparatus which combine infrared laser ablation (LA) with electrospray ionization (ESI) is described, which is called atmospheric pressure mass spectrometry (APMS).