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Journal ArticleDOI

Amperometric biosensors for detection of the prostate cancer marker (PSA)

TLDR
An amperometric detection procedure for t-PSA using three electrode system in which working electrode (THE AUTHORS) is made of hydroxyethyl cellulose and rhodinised carbon is presented, which is rapid, very easy to use and involves low cost compared with other procedures.
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This article is published in International Journal of Pharmaceutics.The article was published on 2002-05-15. It has received 104 citations till now. The article focuses on the topics: Prostate-specific antigen & Prostate.

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Citations
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Electrochemical Biosensors - Sensor Principles and Architectures

TL;DR: In this article, the most common traditional traditional techniques, such as cyclic voltammetry, chronoamperometry, chronopotentiometry, impedance spectroscopy, and various field-effect transistor based methods are presented along with selected promising novel approaches, including nanowire or magnetic nanoparticle-based biosensing.
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Biosensors for cancer markers diagnosis

TL;DR: This review provides an overview of the biosensor technology available today, areas which are currently being developed and researched for cancer markers diagnosis-and a consideration of future prospects for the technology.
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Biosensors and chemosensors based on the optical responses of polydiacetylenes

TL;DR: This tutorial review highlights the recent advances in bio- and chemo-sensors derived from polydiacetylenes and develops efficient sensory systems based on PDAs.
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Biosensor developments : application to prostate-specific antigen detection

TL;DR: This review highlights the current and novel analytical technologies used for PSA detection, which will benefit clinicians, patients and forensic workers in the future.
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Electrochemical and chemiluminescent immunosensors for tumor markers.

TL;DR: This brief review focuses on the current research of immunosensors for tumor markers based on the electrochemical and chemiluminescent detection with emphasis on recent advances, challenges, and trends.
References
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Journal ArticleDOI

Prostate-specific antigen in screening of prostate cancer.

TL;DR: Although the increase in the patient's survival due to PSA‐based detection of early prostate cancer remains to be documented, it is generally agreed that the PSA test along with digital rectal examination (DRE) should be included in the annual physical examination for men 50 years of age or older.
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Validation of a 10-minute dipstick test for serum prostate-specific antigen.

TL;DR: This semiquantitative one-step PSA test is capable of distinguishing serum PSA levels with a cutoff value of 4.0 ng/ml with an overall concordance rate of 92.9%.
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A comparison of three fluorophores for use in an optical biosensor for the measurement of prostate-specific antigen in whole blood

TL;DR: Three fluorophores, allophycocyanin (APC), carboxymethylindocyanine succinimidyl ester (C45) and fluorescein isothiocyanate (FITC), were evaluated in whole blood and serum assays using the fluorescence capillary fill device immunosensor and APC gave the best analytical performance.
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One-step separation-free amperometric biosensor for the detection of protein

TL;DR: A novel enzyme biosensor for the detection of protein that works with only 40 μl of sample per detection, and may be used on-site as a disposable sensor using a hand-held meter.
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Equivalent recognition of free and act‐complexed PSA in a monoclonal‐polyclonal sandwich assay is conferred by binding specificity of the monoclonal antibody

TL;DR: The Bayer Immuno 1TM PSA Assay measures free and ACT‐complexed PSA on an equimolar basis, although it uses a monoclonal antibody (MM1) for capture and polyclonal antibodies for detection, although the affinity constants of MM1 for both free PSA and PSA‐ACT are similar.
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