Journal ArticleDOI
An intense potassium uptake into astrocytes, its further enhancement by high concentrations of potassium, and its possible involvement in potassium homeostasis at the cellular level
TLDR
The purpose of the present study has been directly to measure uptake linflux) of potassium, at different external concentrations, into a population of isolated glial cells which functionally and metabolically are as normal as possible.About:
This article is published in Brain Research.The article was published on 1978-04-21. It has received 122 citations till now. The article focuses on the topics: Potassium & Neuroglia.read more
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The two patterns of reactive astrocytosis in postischemic rat brain.
TL;DR: The results show that astrocyte expression of vimentin is more specific than GFAP in identifying regions of permanent ischemic injury during the early postischemic period and is associated with hyperplasia, as well as hypertrophy.
Journal ArticleDOI
Ion Regulation in the Brain: Implications for Pathophysiology
TL;DR: Computer simulation confirmed that elevation of [K+]o can lead to such a vicious circle and ignite seizures, spreading depression (SD), or hypoxic SD-likedepolarization (anoxic depolarization)
Journal ArticleDOI
Alpha-crystallin as a molecular chaperone.
Barry K. Derham,John J. Harding +1 more
TL;DR: After a substantial amount of chemical data and models, cryo-EM images of alpha-crystallin have confirmed a variable 3D surface with a hollow interior and an age-dependent decrease in chaperone function.
Journal ArticleDOI
Glia-neuron intercommunications and synaptic plasticity.
TL;DR: Astrocytes can be expected to modify the expression of endogenous neurotoxins and thus contribute to synaptic plasticity in ageing and their role in neuronal cell death during ageing and neurodegeneration can only be speculated.
References
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Journal Article
Protein Measurement with the Folin Phenol Reagent
TL;DR: Procedures are described for measuring protein in solution or after precipitation with acids or other agents, and for the determination of as little as 0.2 gamma of protein.
Journal ArticleDOI
Spreading depression of activity in the cerebral cortex
TL;DR: In this article, an interesting response elicited by electrical stimulation was noticed in the cortex of rabbits, and the distinctive feature of this response was a marked, enduring reduction of the "spontaneous" electrical activity of the cortex.
Journal Article
Growth and cultivation of dissociated neurons and glial cells from embryonic chick, rat and human brain in flask cultures
Booher J,Sensenbrenner M +1 more
Book
The mechanism and applications of Leão's spreading depression of electroencephalographic activity
Journal ArticleDOI
Glial cell function: Active control of extracellular K+ concentration
TL;DR: The glial cell Na+ K+-ATPase was always more active, and markedly more sensitive to variations in the K+ ion concentration than the neuronal ATPase, which support the idea that control of the extracellular K- ion concentration in the CNS is at least in part dependent on the metabolically coupled sodium-potassium pump of the glia.