Journal ArticleDOI
Analgesic Effects of an Ethanol Extract of the Fruits of Xylopia aethiopica and Xylopic Acid in Murine Models of Pain: Possible Mechanism(s)
Eric Woode,Elvis Ofori Ameyaw,George K. Ainooson,Wonder Kofi Mensah Abotsi,Eric Boakye-Gya,James Oppong Kyekyeku +5 more
- Vol. 4, Iss: 4, pp 285-300
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The article was published on 2013-04-01. It has received 18 citations till now. The article focuses on the topics: Xylopia aethiopica.read more
Citations
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Journal ArticleDOI
Anti-allodynic and Anti-hyperalgesic effects of an ethanolic extract and xylopic acid from the fruits of Xylopia aethiopica in murine models of neuropathic pain.
Elvis Ofori Ameyaw,Eric Woode,Eric Boakye-Gyasi,Wonder Kofi Mensah Abotsi,James Oppong Kyekyeku,Reimmel Kwame Adosraku +5 more
TL;DR: These findings establish the anti-allodynic and anti-hyperalgesic effects of the ethanolic fruit XAE and its major diterpene XA in vincristine-induced neuropathtic pain.
Journal ArticleDOI
Xylopia aethiopica fruit extract exhibits antidepressant-like effect via interaction with serotonergic neurotransmission in mice
TL;DR: This study shows that Xylopia aethiopica has antidepressant potential largely due to effects on 5-HT neurotransmission with possible glutamatergic effect through the glycineB co-binding site and nitric oxide synthase inhibition.
Journal ArticleDOI
Medicinal plants and their isolated phytochemicals for the management of chemotherapy-induced neuropathy: therapeutic targets and clinical perspective.
Vahideh Oveissi,Vahideh Oveissi,Mahboobe Ram,Roodabeh Bahramsoltani,Farnaz Ebrahimi,Roja Rahimi,Rozita Naseri,Tarun Belwal,Hari Prasad Devkota,Zahra Abbasabadi,Mohammad Hosein Farzaei +10 more
TL;DR: There are currently limited clinical evidence on medicinal plants for CIPN which shows the necessity of future mechanistic studies, as well as well-designed clinical trial for further confirmation of the safety and efficacy of herbal medicines in CIPn.
Journal ArticleDOI
An isobolographic analysis of the antinociceptive effect of xylopic acid in combination with morphine or diclofenac.
TL;DR: In conclusion, the present study demonstrated synergism for the co-administration of XA with morphine or diclofenac for the combination of analgesics.
Journal ArticleDOI
Effects of an ethanol extract and the diterpene, xylopic acid, of Xylopia aethiopica fruits in murine models of musculoskeletal pain
Eric Woode,Elvis Ofori Ameyaw,Eric Boakye-Gyasi,Wonder Kofi Mensah Abotsi,James Oppong Kyekyeku,Reimmel Kwame Adosraku,Robert Peter Biney +6 more
TL;DR: These findings establish analgesic properties of the ethanol fruit extract of X. aethiopica and xylopic acid in musculoskeletalPain models, which significantly reduced the spread of hyperalgesia to contralateral limbs in both models of chronic hyperAlgesia.
References
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