Open AccessDissertation
Analysis of the mechanism(s) of immunological tolerance to a physiological soluble antigen in transgenic mice
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The article was published on 1997-01-01 and is currently open access. It has received 1 citations till now.read more
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Limiting Dilution Analysis of Cells in the Immune System
TL;DR: This book is clearly not intended for diagnostic histopathologists except for those with a special interest in the lymphoreticular system and neoplasms of that system and those who have good library facilities available will need to judge for themselves whether they consider it worthwhile paying £16-50 for having a literature survey covering that system.
References
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Journal ArticleDOI
Functional diversity of helper T lymphocytes.
TL;DR: The existence of subsets of CD4+ helper T lymphocytes that differ in their cytokine secretion patterns and effector functions provides a framework for understanding the heterogeneity of normal and pathological immune responses.
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T cell tolerance by clonal elimination in the thymus
TL;DR: The results show that in normal animals tolerance to self-MHC is due to clonal elimination rather than suppression, and indicate that tolerance induction may occur in the thymus at the time immature thymocytes are selected to move into the mature thymocyte pool.
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Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis
TL;DR: Mucosally derived TH2-like clones induced by oral antigen can actively regulate immune responses in vivo and may represent a different subset of T cells.
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Tolerance in T-cell-receptor transgenic mice involves deletion of nonmature CD4 + 8 + thymocytes
TL;DR: The mechanism of self-tolerance is studied in T-cell-receptor transgenic mice expressing a receptor in many of their T cells for the male (H–Y) antigen in the context of class I H–2Db MHC antigens.
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Differing lymphokine profiles of functional subsets of human CD4 and CD8 T cell clones.
Padmini Salgame,John S. Abrams,Carol Clayberger,Harris Goldstein,Jacinto Convit,Robert L. Modlin,Barry R. Bloom +6 more
TL;DR: Functional subsets of human T cells were delineated by analyzing patterns of lymphokines produced by clones from individuals with leprosy and by T cell clones of known function, and interleukin-4 was found to be necessary for suppression in vitro.