Journal ArticleDOI
Anaphylaxis during anesthesia in France: An 8-year national survey
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The incidence of allergic reactions during anesthesia, estimated on a national basis, is higher than previously estimated and the similar incidence of reactions according to sex before adolescence suggests a role for sex hormones in the increase of anaphylaxis observed in women.Abstract:
Background More attention should be paid to rare serious adverse events such as anaphylaxis to increase the safety of anesthesia. Objective To report the results of an 8-year survey of anaphylaxis during anesthesia in France. Methods Data from patients who experienced anaphylaxis between January 1, 1997, and December 31, 2004, were analyzed. Estimated incidences were obtained by combining this database with data from the French pharmacovigilance system by using a capture-recapture method. The number of patients exposed to the offending agents was obtained from data collected during the national survey of anesthesia practice. Results A total of 2516 patients was included. A diagnosis of IgE-mediated reaction was established in 1816 cases (72.18%). The most common causes were neuromuscular blocking agents ([NMBAs]; n = 1067; 58.08%), latex (n = 361; 19.65%), and antibiotics (n = 236; 12.85%). The median annual incidence per million procedures was higher for females 154.9 (5th-95th percentile, 117.2-193.1) than for males 55.4 (5th-95th percentile, 42.0-68.0). It reached 250.9 (5th-95th percentile, 189.8-312.9) for women in cases of allergic reactions to NMBAs. In children, a diagnosis of IgE-mediated reactions was obtained in 122 cases (45.9%). The most common causes were latex (n = 51; 41.8%), NMBAs (n = 39; 31.97%), and antibiotics (n = 11; 9.02%). In contrast with adults, no female predominance was observed. Conclusion The incidence of allergic reactions during anesthesia, estimated on a national basis, is higher than previously estimated. These results should be taken into account in the evaluation of the benefit-to-risk ratio of the various anesthetic techniques in individuals. The similar incidence of reactions according to sex before adolescence suggests a role for sex hormones in the increase of anaphylaxis observed in women.read more
Citations
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Severe anaphylaxis to Propofol: first case of evidence of sensitization to soy oil.
TL;DR: A case of anaphylaxis to propofol in an adult patient without food allergy to soy, but with a latent sensitization to soy is reported and a systematic detection for proteins in the refined soybean oil used in the pharmaceutical industry for intravenous products is recommended.
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Perioperative anaphylaxis: pathophysiology, clinical presentation and management.
Pascale Dewachter,L. Savic +1 more
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Anaphylactic bronchospasm during general anesthesia is not related to asthma
Aurélie Gouel-Chéron,C. Neukirch,B. Aubier,Philippe Montravers,P Nicaise,Sylvie Chollet-Martin,Paul-Michel Mertes,Michel Aubier,Dan Longrois +8 more
TL;DR: The results suggest that the mechanisms of bronchospasm in AS may be different from those of asthma and that, in the presence of bron chospasm during anesthesia, AS should be considered to be the most likely cause.
Journal ArticleDOI
Time to achieve target mean arterial pressure during resuscitation from experimental anaphylactic shock in an animal model. A comparison of adrenaline alone or in combination with different volume expanders.
K Tajima,F. Zheng,O. Collange,G Barthel,S N Thornton,D Longrois,D Longrois,Bruno Levy,G Audibert,J.-M. Malinovsky,P M Mertes +10 more
TL;DR: The results support the combined use of adrenaline and volume expansion for resuscitation from anaphylactic shock, and when used with adrenaline the most effective fluid was hydroxyethyl starch, whereas hypertonic saline was the least effective.
Journal ArticleDOI
Oxytocin: an unexpected risk for cardiologic and broncho-obstructive effects, and allergic reactions in susceptible delivering women.
Gennaro Liccardi,Maria Beatrice Bilò,Ciro Mauro,Antonello Salzillo,Amedeo Piccolo,Maria D'Amato,Annabella Liccardi,Gennaro D'Amato +7 more
TL;DR: There is a need of particular attention in managing delivering women suffering from latex allergy and bronchial asthma, with accurate anamnestic, clinical and diagnostic evaluation, latex-free anesthesiological setting, use of oxytocin-alternative agents and, if necessary, a drug premedication are likely to reduce the risk of anaphylactic/broncho-obstructive reactions in these women.
References
More filters
Journal ArticleDOI
Incidence of Adverse Drug Reactions in Hospitalized Patients: A Meta-analysis of Prospective Studies
TL;DR: The incidence of serious and fatal adverse drug reactions in US hospitals was found to be extremely high, and data suggest that ADRs represent an important clinical issue.
Journal ArticleDOI
Revised nomenclature for allergy for global use: Report of the Nomenclature Review Committee of the World Allergy Organization, October 2003.
S.G.O. Johansson,Thomas Bieber,Ronald Dahl,Peter S. Friedmann,Bobby Q. Lanier,Richard F. Lockey,C. Motala,José Antonio Ortega Martell,Thomas A.E. Platts-Mills,Johannes Ring,Frank P Thien,Paul Van Cauwenberge,Hywel C Williams +12 more
TL;DR: The nomenclatures proposed in the October 2003 report of the Nomenclature Review Committee of the World Allergy Organization is an update of the European Academy of Allergology and Clinical Immunology Revised NomenClature for Allergy Position Statement published in 2001.
Book
Monte Carlo: Concepts, Algorithms, and Applications
TL;DR: This paper presents a meta-modelling framework that automates the very labor-intensive and therefore time-heavy and expensive process of manually cataloging samples and generating random numbers.
Journal ArticleDOI
Prevention of Infective Endocarditis Guidelines From the American Heart Association: A Guideline From the American Heart Association Rheumatic Fever, Endocarditis, and Kawasaki Disease Committee, Council on Cardiovascular Disease in the Young, and the Council on Clinical Cardiology, Council on Cardiovascular Surgery and Anesthesia, and the Quality of Care and Outcomes Research Interdisciplinary Working Group
Walter R. Wilson,Kathryn A. Taubert,Michael H. Gewitz,Peter B. Lockhart,Larry M. Baddour,Matthew E. Levison,Ann F. Bolger,Christopher H. Cabell,Masato Takahashi,Robert S. Baltimore,Jane W. Newburger,Brian L. Strom,Lloyd Y. Tani,Michael A. Gerber,Robert O. Bonow,Thomas J. Pallasch,Stanford T. Shulman,Anne H. Rowley,Jane C. Burns,Patricia Ferrieri,Timothy J. Gardner,David Goff,David T. Durack +22 more
TL;DR: In this article, the authors updated the recommendations by the American Heart Association (AHA) for the prevention of infective endocarditis that were last published in 1997, and the purpose of this statement is to update the recommendations.
Journal ArticleDOI
A revised nomenclature for allergy. An EAACI position statement from the EAACI nomenclature task force.
S.G.O. Johansson,J. O'b. Hourihane,Jean Bousquet,Carla A.F.M. Bruijnzeel-Koomen,Sten Dreborg,Tari Haahtela,Marek L. Kowalski,N. Mygind,Johannes Ring,P. Van Cauwenberge,M. van Hage-Hamsten,Brunello Wüthrich +11 more
TL;DR: In this paper, the authors proposed a revised nomenclature for allergic and related reactions that can be used independently of target organ or patient age group, based on the present knowledge of the mechanisms which initiate and mediate allergic reactions.
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