Journal ArticleDOI
Anaphylaxis during anesthesia in France: An 8-year national survey
TLDR
The incidence of allergic reactions during anesthesia, estimated on a national basis, is higher than previously estimated and the similar incidence of reactions according to sex before adolescence suggests a role for sex hormones in the increase of anaphylaxis observed in women.Abstract:
Background More attention should be paid to rare serious adverse events such as anaphylaxis to increase the safety of anesthesia. Objective To report the results of an 8-year survey of anaphylaxis during anesthesia in France. Methods Data from patients who experienced anaphylaxis between January 1, 1997, and December 31, 2004, were analyzed. Estimated incidences were obtained by combining this database with data from the French pharmacovigilance system by using a capture-recapture method. The number of patients exposed to the offending agents was obtained from data collected during the national survey of anesthesia practice. Results A total of 2516 patients was included. A diagnosis of IgE-mediated reaction was established in 1816 cases (72.18%). The most common causes were neuromuscular blocking agents ([NMBAs]; n = 1067; 58.08%), latex (n = 361; 19.65%), and antibiotics (n = 236; 12.85%). The median annual incidence per million procedures was higher for females 154.9 (5th-95th percentile, 117.2-193.1) than for males 55.4 (5th-95th percentile, 42.0-68.0). It reached 250.9 (5th-95th percentile, 189.8-312.9) for women in cases of allergic reactions to NMBAs. In children, a diagnosis of IgE-mediated reactions was obtained in 122 cases (45.9%). The most common causes were latex (n = 51; 41.8%), NMBAs (n = 39; 31.97%), and antibiotics (n = 11; 9.02%). In contrast with adults, no female predominance was observed. Conclusion The incidence of allergic reactions during anesthesia, estimated on a national basis, is higher than previously estimated. These results should be taken into account in the evaluation of the benefit-to-risk ratio of the various anesthetic techniques in individuals. The similar incidence of reactions according to sex before adolescence suggests a role for sex hormones in the increase of anaphylaxis observed in women.read more
Citations
More filters
Journal ArticleDOI
Effect of body mass index and rocuronium on serum tryptase concentration during volatile general anesthesia: an observational study.
TL;DR: Excess weight and obesity predispose to higher preoperative serum tryptase values, and postoperative STC is not linked to rocuronium doses.
Journal ArticleDOI
Hypersensitivity Reaction to Midazolam
TL;DR: A case of a six year old child who presented a hypersensitivity skin reaction to midazolam thirty minutes after intrarectal midAZolam administration is described, a generalized rash of the whole body without pruritis.
Journal ArticleDOI
Anafilaxia por corante azul patente V: relato de caso e revisão da literatura
TL;DR: In this article, a reacao anafilaxia pode ocorrer durante o periodo perioperatorio devido a exposicao a diversos agentes capazes de induzir reacoes de hipersensibilidade.
Journal ArticleDOI
Modified fluid gelatin 4% for perioperative volume replacement in pediatric patients (GPS): Results of a European prospective noninterventional multicenter study
Robert Sümpelmann,Anna Camporesi,Ignacio Galvez,Dimitar Pechilkov,Christoph Eich,Franz-Josef Kretz,Remei Perera Sarri,D Tancheva,S. Serrano-Casabon,P.J. Murphy,Marinella Astuto,Clelia Zanaboni,Karin Becke,Nils Dennhardt +13 more
TL;DR: A European prospective noninterventional multicenter study to evaluate the use of a modified fluid gelatin 4% in saline (sal‐GEL) or an acetate‐containing balanced electrolyte solution (bal‐Gels) in children undergoing major pediatric surgery.
Journal ArticleDOI
Enquête sur la prise en charge des chocs anaphylactiques aux curares auprès des anesthésistes-réanimateurs de la région Picardie : de la déclaration à la consultation d’allergologie
Sophie Romby,Stéphanie Malaquin,Mélanie Perquin,Louise Badoux,Mélanie Levrard,Yazine Mahjoub,Nacim Ammenouche,François Tinturier,Norair Airapetian,Emmanuel Lorne,Hervé Dupont +10 more
TL;DR: In this article, the authors evaluated the qualite de the sous-declaration of a choc anaphylactique (CA) made by a medecin anesthesistes-reanimateurs (MAR) at the centre regional de pharmacovigilance.
References
More filters
Journal ArticleDOI
Incidence of Adverse Drug Reactions in Hospitalized Patients: A Meta-analysis of Prospective Studies
TL;DR: The incidence of serious and fatal adverse drug reactions in US hospitals was found to be extremely high, and data suggest that ADRs represent an important clinical issue.
Journal ArticleDOI
Revised nomenclature for allergy for global use: Report of the Nomenclature Review Committee of the World Allergy Organization, October 2003.
S.G.O. Johansson,Thomas Bieber,Ronald Dahl,Peter S. Friedmann,Bobby Q. Lanier,Richard F. Lockey,C. Motala,José Antonio Ortega Martell,Thomas A.E. Platts-Mills,Johannes Ring,Frank P Thien,Paul Van Cauwenberge,Hywel C Williams +12 more
TL;DR: The nomenclatures proposed in the October 2003 report of the Nomenclature Review Committee of the World Allergy Organization is an update of the European Academy of Allergology and Clinical Immunology Revised NomenClature for Allergy Position Statement published in 2001.
Book
Monte Carlo: Concepts, Algorithms, and Applications
TL;DR: This paper presents a meta-modelling framework that automates the very labor-intensive and therefore time-heavy and expensive process of manually cataloging samples and generating random numbers.
Journal ArticleDOI
Prevention of Infective Endocarditis Guidelines From the American Heart Association: A Guideline From the American Heart Association Rheumatic Fever, Endocarditis, and Kawasaki Disease Committee, Council on Cardiovascular Disease in the Young, and the Council on Clinical Cardiology, Council on Cardiovascular Surgery and Anesthesia, and the Quality of Care and Outcomes Research Interdisciplinary Working Group
Walter R. Wilson,Kathryn A. Taubert,Michael H. Gewitz,Peter B. Lockhart,Larry M. Baddour,Matthew E. Levison,Ann F. Bolger,Christopher H. Cabell,Masato Takahashi,Robert S. Baltimore,Jane W. Newburger,Brian L. Strom,Lloyd Y. Tani,Michael A. Gerber,Robert O. Bonow,Thomas J. Pallasch,Stanford T. Shulman,Anne H. Rowley,Jane C. Burns,Patricia Ferrieri,Timothy J. Gardner,David Goff,David T. Durack +22 more
TL;DR: In this article, the authors updated the recommendations by the American Heart Association (AHA) for the prevention of infective endocarditis that were last published in 1997, and the purpose of this statement is to update the recommendations.
Journal ArticleDOI
A revised nomenclature for allergy. An EAACI position statement from the EAACI nomenclature task force.
S.G.O. Johansson,J. O'b. Hourihane,Jean Bousquet,Carla A.F.M. Bruijnzeel-Koomen,Sten Dreborg,Tari Haahtela,Marek L. Kowalski,N. Mygind,Johannes Ring,P. Van Cauwenberge,M. van Hage-Hamsten,Brunello Wüthrich +11 more
TL;DR: In this paper, the authors proposed a revised nomenclature for allergic and related reactions that can be used independently of target organ or patient age group, based on the present knowledge of the mechanisms which initiate and mediate allergic reactions.
Related Papers (5)
Skin test concentrations for systemically administered drugs -- an ENDA/EAACI Drug Allergy Interest Group position paper
Knut Brockow,Lh Garvey,Werner Aberer,Marina Atanaskovic-Markovic,A. Barbaud,M. B. Bilò,Andreas J. Bircher,Miguel Blanca,B Bonadonna,Paolo Campi,E Castro,Jr Cernadas,Am Chiriac,Pascal Demoly,Martine Grosber,J Gooi,Carla Lombardo,Pm Mertes,Holger Mosbech,S Nasser,M. Pagani,J. Ring,Audrey Romano,Kathrin Scherer,B Schnyder,S. Testi,María José Torres,Axel Trautmann,Ingrid Terreehorst +28 more