Antioxidant and free radical scavenging activities of Terminalia chebula.
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TLDR
All tested extracts and pure compounds of T. chebula exhibited antioxidant activity at different magnitudes of potency, and the antioxidant activity of each pure compound was derived from different pathways and was suggested to be specific.Abstract:
Free radicals react with biological molecules and destroy the structure of cells, which eventually causes free-radical induced disease such as cancer, renal failure, aging, etc. In this study, 6 extracts and 4 pure compounds of Terminalia chebula RETZ. were investigated for anti-lipid peroxidation, anti-superoxide radical formation and free radical scavenging activities. The superoxide radical scavenging of the 4 pure compounds was further evaluated using electron spin resonance (ESR) spectrometry. The results showed that all tested extracts and pure compounds of T. chebula exhibited antioxidant activity at different magnitudes of potency. The antioxidant activity of each pure compound was derived from different pathways and was suggested to be specific.read more
Citations
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Antioxidant approach to disease management and the role of ‘Rasayana’ herbs of Ayurveda
TL;DR: 'Rasayana' plants with potent antioxidant activity have been reviewed for their traditional uses, and mechanism of antioxidant action, and the role of free radicals in these diseases has been briefly reviewed.
Journal ArticleDOI
Polyphenolic compounds in the fruits of Egyptian medicinal plants (Terminalia bellerica, Terminalia chebula and Terminalia horrida): characterization, quantitation and determination of antioxidant capacities.
B. Pfundstein,Samy K. El Desouky,William E. Hull,Roswitha Haubner,Gerhard Erben,Robert W. Owen +5 more
TL;DR: Antioxidant capacities of the raw fruit extracts and the major isolated substances were determined and indicated that chebulic ellagitannins have high activity which may correlate with high potential as cancer chemopreventive agents.
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Antioxidant and free radical scavenging activities of wild bitter melon (Momordica charantia Linn. var. abbreviata Ser.) in Taiwan
Shu-Jing Wu,Lean-Teik Ng +1 more
TL;DR: Results showed that BM extracts possess potent antioxidant and free radical scavenging activities, which could have contributed, at least partly, to the therapeutic benefits of the certain traditional claims of wild BM.
Journal ArticleDOI
Comparative study of the antioxidant and reactive oxygen species scavenging properties in the extracts of the fruits of Terminalia chebula, Terminalia belerica and Emblica officinalis
TL;DR: The in vitro antioxidant and reactive oxygen species scavenging activities of Terminalia chebula, Terminalia belerica and Emblica officinalis fruit extracts showed quite good efficacy in their antioxidant and radical scavenging abilities, compared to the standards.
Journal ArticleDOI
Antidiabetic and renoprotective effects of the chloroform extract of Terminalia chebula Retz. seeds in streptozotocin-induced diabetic rats.
TL;DR: The results indicate a prolonged action in reduction of blood glucose by T. chebula and is probably mediated through enhanced secretion of insulin from the β-cells of Langerhans or through extra pancreatic mechanism.
References
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Joe M. McCord,Irwin Fridovich +1 more
TL;DR: The demonstration that O2·- can reduce ferricytochrome c and tetranitromethane, and that superoxide dismutase, by competing for the superoxide radicals, can markedly inhibit these reactions, is demonstrated.
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Role of Oxidative Stress in Development of Complications in Diabetes
TL;DR: Structural characterization of the cross-links and other products accumulating in collagen in diabetes is needed to gain a better understanding of the relationship between oxidative stress and the development of complications in diabetes.
Book
Medicinal Plants of East and Southeast Asia: Attributed Properties and Uses
Lily M. Perry,Judith Metzger +1 more
TL;DR: In "Medicinal Plants of East and Southeast Asia, " the medicinal properties of "Acanthus ilicifolius" are described along with those of hundreds of other plants.
Journal ArticleDOI
Anti-diabetic activity of medicinal plants and its relationship with their antioxidant property.
M C Sabu,Ramadasan Kuttan +1 more
TL;DR: Methanolic extract of Terminalia chebula, Terminalia belerica, Emblica officinalis and their combination named 'Triphala' (equal proportion of above three plant extracts) were found to inhibit lipid peroxide formation and to scavenge hydroxyl and superoxide radicals in vitro.