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Journal ArticleDOI

Are Hygromas and Hydrocephalus After Decompressive Craniectomy Caused by Impaired Brain Pulsatility, Cerebrospinal Fluid Hydrodynamics, and Glymphatic Drainage? Literature Overview and Illustrative Cases.

Paul T. Akins, +1 more
- 11 Jul 2019 - 
- Vol. 130
TLDR
Closure of the cranial defect with cranioplasty improves cerebral blood flow and CSF pulsatile circulation and is frequently sufficient to resolve the external hydrocephalus.
About
This article is published in World Neurosurgery.The article was published on 2019-07-11. It has received 25 citations till now. The article focuses on the topics: Decompressive craniectomy & Hydrocephalus.

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Citations
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First-in-human experience with integration of wireless intracranial pressure monitoring device within a customized cranial implant

TL;DR: This first-in-human experience demonstrates a newfound safety and efficacy of integrating a wireless ICP sensor within a CCI for perioperative neuromonitoring, and proven restoration of normal ICP postcranioplasty despite severe preoperative transcranial herniation.
Journal ArticleDOI

Predictive Factors of Surgical Site Infection Following Cranioplasty: A Study Including 3D Printed Implants.

TL;DR: In this paper, the authors identify predictive factors for Surgical Site Infection following decompressive craniectomy (DC) by reviewing procedures performed over a 10-year period and provide guidelines associated with the procedure.
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Concurrent Versus Staged Procedures for Ventriculoperitoneal Shunt and Cranioplasty: A 10-Year Retrospective Comparative Analysis of Surgical Outcomes.

TL;DR: Because of the trend toward a reduced reoperation rate, the significantly reduced rate of hospital-acquired infection, and the reduction in the number of surgeries, this study recommends that patients awaiting cranioplasty in the setting of persistent hydrocephalus undergo concurrent VPS placement and crANIoplasty rather than staged procedures.
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Does Impaired Glymphatic Drainage Cause Glymphedema? A Review Tailored to Neurocritical Care and Neurosurgery.

TL;DR: In this paper, the authors provide an overview of key discoveries of the glymphatic system, which promotes bulk flow of fluid and solutes throughout the brain parenchyma, and discuss the lymphatic drainage of the central nervous system.
References
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Journal ArticleDOI

Structural and functional features of central nervous system lymphatic vessels

TL;DR: In searching for T-cell gateways into and out of the meninges, functional lymphatic vessels lining the dural sinuses are discovered, which may call for a reassessment of basic assumptions in neuroimmunology and sheds new light on the aetiology of neuroinflammatory and neurodegenerative diseases associated with immune system dysfunction.
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Cerebral Arterial Pulsation Drives Paravascular CSF–Interstitial Fluid Exchange in the Murine Brain

TL;DR: It is demonstrated that cerebral arterial pulsatility is a key driver of paravascular CSF influx into and through the brain parenchyma, and suggested that changes in arterials pulsatility may contribute to accumulation and deposition of toxic solutes, including amyloid β, in the aging brain.
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The glymphatic pathway in neurological disorders

TL;DR: The observed reduction in CSF clearance was associated with increasing grey-matter concentrations of Aβ in the human brain, consistent with findings in mice showing that decreased glymphatic function leads to Aβ accumulation and the development of neurodegenerative diseases.
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Outcome following decompressive craniectomy for malignant swelling due to severe head injury.

TL;DR: Decompressive craniectomy was associated with a better-than-expected functional outcome in patients with medically uncontrollable ICP and/or brain herniation, compared with outcomes in other control cohorts reported on in the literature.
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Evidence of connections between cerebrospinal fluid and nasal lymphatic vessels in humans, non-human primates and other mammalian species

TL;DR: Comparing the CSF and nasal lymph associations in human and non-human primates with those observed in other mammalian species suggested that CSF absorption into nasal lymphatics is a characteristic feature of all mammals including humans.
Trending Questions (1)
What are the causes of hydrocephalus after brain surgery?

The paper suggests that hydrocephalus after decompressive craniectomy may be caused by reduced internal brain expansion, impaired cerebrospinal fluid flow, reduced clearance of interstitial fluid, and redistribution of CSF.