Assessing BDNF as a mediator of the effects of exercise on depression.
Kristin L. Szuhany,Michael Otto +1 more
TLDR
Overall, this study adds to the literature showing reliable effects of acute exercise on increasing BDNF and extends this research to the infrequently studied depressed population, but does not clarify the mechanism behind exercise benefits for depression.About:
This article is published in Journal of Psychiatric Research.The article was published on 2020-02-08 and is currently open access. It has received 35 citations till now. The article focuses on the topics: Brain-derived neurotrophic factor & Behavioral activation.read more
Citations
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Blood Brain-Derived Neurotrophic Factor (BDNF) and Major Depression: Do We Have a Translational Perspective?
TL;DR: In this article, a review of the literature regarding BDNF function, genetics and epigenetics, expression, and results from clinical trials is summarized, putting the literature into a translational perspective on major depressive disorder.
Journal ArticleDOI
The Effects and Mechanisms of Exercise on the Treatment of Depression.
TL;DR: A systematic review of English language literature including papers published from 2010 to present in PubMed was performed to investigate the feasibility and efficacy of exercise therapy for patients with depression, in order to appraise the evidence and outline accepted guidelines to direct individualized treatment plans.
Journal ArticleDOI
BDNF Impact on Biological Markers of Depression-Role of Physical Exercise and Training.
Eugenia Murawska-Ciałowicz,Mona Wiatr,Maria Ciałowicz,Gilmara Gomes de Assis,Wojciech Borowicz,Sílvia Rocha-Rodrigues,Małgorzata Paprocka-Borowicz,Adilson Marques +7 more
TL;DR: In this paper, the effects of exercise training on BNDF expression and how it impacts depression as well as the potential mechanisms mediating this process, providing a better understanding of underlying ET-related mechanisms in depression.
Journal ArticleDOI
The role of exercise in the treatment of depression: biological underpinnings and clinical outcomes
Journal ArticleDOI
Antioxidant Biomolecules and Their Potential for the Treatment of Difficult-to-Treat Depression and Conventional Treatment-Resistant Depression
TL;DR: The preclinical and clinical evidence showing the potential effects of different antioxidant and anti-inflammatory biomolecules as antidepressants, with a focus on difficult-to-treat depression and conventional treatment-resistant depression are evaluated.
References
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Journal ArticleDOI
A new depression scale designed to be sensitive to change.
Stuart Montgomery,Marie Åsberg +1 more
TL;DR: The construction of a depression rating scale designed to be particularly sensitive to treatment effects is described, and its capacity to differentiate between responders and non-responders to antidepressant treatment was better than the HRS, indicating greater sensitivity to change.
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Aerobic exercise and neurocognitive performance: a meta-analytic review of randomized controlled trials.
Patrick Smith,James A. Blumenthal,Benson M. Hoffman,Harris Cooper,Timothy A. Strauman,Kathleen A. Welsh-Bohmer,Jeffrey N. Browndyke,Andrew Sherwood +7 more
TL;DR: Aerobic exercise training is associated with modest improvements in attention and processing speed, executive function, and memory, although the effects of exercise on working memory are less consistent.
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Assessment of habitual physical activity by a seven-day recall in a community survey and controlled experiments.
Steven N. Blair,William L. Haskell,Ping Ho,Ralph S. Paffenbarger,Karen Vranizan,John W. Farquhar,Peter D. Wood +6 more
TL;DR: The physical activity recall provides useful estimates of habitual physical activity for research in epidemiologic and health education studies, and changes in energy expenditure were associated with changes in maximal oxygen uptake and body fatness.
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Serum brain-derived neurotrophic factor, depression, and antidepressant medications: meta-analyses and implications.
TL;DR: Findings provide strong evidence to suggest that serum BDNF levels are abnormally low in patients suffering from major depressive disorder and that the BDNF Levels are elevated following a course of antidepressant treatment.