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Open AccessJournal ArticleDOI

Assessment of clinical practice guideline methodology for the treatment of knee osteoarthritis with intra-articular hyaluronic acid.

TLDR
There is a need for a standard "appropriate methodology" that is agreed upon for osteoarthritis clinical practice guidelines in order to prevent the development of conflicting recommendations for intra-articular hyaluronic acid treatment for knee osteOarthritis.
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This article is published in Seminars in Arthritis and Rheumatism.The article was published on 2015-10-01 and is currently open access. It has received 69 citations till now. The article focuses on the topics: Guideline.

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Citations
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Journal ArticleDOI

Cartilage repair in degenerative osteoarthritis mediated by squid type II collagen via immunomodulating activation of M2 macrophages, inhibiting apoptosis and hypertrophy of chondrocytes

TL;DR: It is shown that SCII immunomodulates M2 activation of macrophages to skew the local OA microenvironment towards a pro-chondrogenic atmosphere, and promotes cartilage repair under inflammatory condition, which shows great potential for SCII to be a novel biomaterial for cartilage Repair in OA.
Journal ArticleDOI

Why we should definitely include intra-articular hyaluronic acid as a therapeutic option in the management of knee osteoarthritis: Results of an extensive critical literature review.

TL;DR: IAHA may offer one of the best benefit/risk ratios among pharmacologic options, as measured by improvements in knee OA health outcomes, overall gain in quality-adjusted life years and substantial delays in time to total knee replacement.
Journal ArticleDOI

Guideline appraisal with AGREE II: Systematic review of the current evidence on how users handle the 2 overall assessments.

TL;DR: The 2 overall assessments of AGREE II are underreported by guideline assessors, and domain 3 (rigour of development) has the strongest influence on the results of the 2 Overall assessments, while the other domains have a varying influence.
Journal ArticleDOI

Intra-articular Hyaluronic Acid in Treating Knee Osteoarthritis: a PRISMA-Compliant Systematic Review of Overlapping Meta-analysis.

TL;DR: The present systematic review of overlapping meta-analyses demonstrates that HA is an effective intervention in treating knee OA without increased risk of adverse events, and may help decision makers interpret and choose among discordant meta-Analyses.
References
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A systematic review of the literature

TL;DR: Physicians should consider modification of immunosuppressive regimens to decrease the risk of PTD in high-risk transplant recipients and Randomized trials are needed to evaluate the use of oral glucose-lowering agents in transplant recipients.
Journal ArticleDOI

Clinical guidelines: potential benefits, limitations, and harms of clinical guidelines.

TL;DR: The potential benefits, limitations, and harms of clinical guidelines are examined, a tool for making care more consistent and efficient and for closing the gap between what clinicians do and what scientific evidence supports.
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