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Journal ArticleDOI

Association of Waking Episodes With Menopausal Hot Flushes

Yohanan Erlik, +5 more
- 01 May 1981 - 
- Vol. 245, Iss: 17, pp 1741-1744
TLDR
The data suggest the menopausal flushes are associated with a chronic sleep disturbance, and both can be improved by estrogen therapy.
Abstract
To examine the possible relationship between the occurrence of menopausal hot flushes and waking episodes, a study was conducted of nine postmenopausal women with severe hot flushes and five asymptomatic premenopausal women. Measurement of simultaneous changes of finger temperature and skin resistance over the sternum was used as an objective marker of hot flushes. During cumulative sleep 47 objectively measured hot flushes occurred, and 45 were associated with a waking episode measured by polygraphic techniques. In eight of nine subjects, a significant correlation was observed between the occurrence of hot flushes and waking episodes. A similar association was not observed in premenopausal subjects. Estrogen administered to symptomatic patients resulted in significant reductions of both hot flushes and waking episodes. These data suggest that menopausal flushes are associated with a chronic sleep disturbance, and both can be improved by estrogen therapy. (JAMA1981;245:1741-1744)

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Citations
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Prevalence, clinical characteristics, and risk factors for insomnia in the context of breast cancer.

TL;DR: Insomnia is a prevalent and often chronic problem in breast cancer patients and although it is not always a direct consequence of cancer, pre-existing sleep difficulties are often aggravated by cancer, it is therefore important to better screen breast cancer Patients with insomnia and offer them an appropriate treatment.
References
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Journal ArticleDOI

A Manual of Standardized Terminology, Techniques and Scoring System for Sleep Stages of Human Subjects.

TL;DR: Techniques of recording, scoring, and doubtful records are carefully considered, and Recommendations for abbreviations, types of pictorial representation, order of polygraphic tracings are suggested.
Journal ArticleDOI

The menopausal syndrome

TL;DR: Results of a postal questionnaire survey of 638 women aged 45 to 54, living in the London area in 1964-65, indicate that hot flushes and night sweats are clearly associated with the onset of a natural menopause and that they occur in the majority of women.
Journal ArticleDOI

Menopausal flushes: a neuroendocrine link with pulsatile luteninizing hormone secreation

TL;DR: Findings suggest a link between the neuroendocrine mechanisms that initiate such episodic secretion and those responsible for the onset of flush episodes.
Journal ArticleDOI

Effects of Estrogens on Sleep and Psychological State of Hypogonadal Women

TL;DR: The administration of estrogens was associated with a shorter mean sleep latency, a longer period of rapid eye movement sleep, and a positive correlation between psychological intactness (as clinically ranked) and latency to sleep onset.
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