Journal ArticleDOI
Attenuation in the control of expression of bacterial operons
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TLDR
Bacterial operons concerned with the biosynthesis of amino acids are often controlled by a process of attenuation, where the amino acid in short supply means translation is stalled at the relevant codons of the transcript long enough for the succeeding segment of the transcripts to form secondary structures that allow the transcribing RNA polymerase molecule to proceed through a site that otherwise dictates termination of transcription.Abstract:
Bacterial operons concerned with the biosynthesis of amino acids are often controlled by a process of attenuation. The translation product of the initial segment of the transcript of each operon is a peptide rich in the amino acid that the particular operon controls. If the amino acid is in short supply translation is stalled at the relevant codons of the transcript long enough for the succeeding segment of the transcript to form secondary structures that allow the transcribing RNA polymerase molecule to proceed through a site that otherwise dictates termination of transcription. This site is the attenuator; the process is attenuation.read more
Citations
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The noncoding RNA revolution-trashing old rules to forge new ones.
TL;DR: The pathway of ncRNA research is described, where every established "rule" seems destined to be overturned.
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The tac promoter: a functional hybrid derived from the trp and lac promoters
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Comparison of initiation of protein synthesis in procaryotes, eucaryotes, and organelles.
TL;DR: The Shine-Dalgarno sequence, appropriately positioned upstream from an exposed initiator codon, is sufficient to define a bacterial ribosome bnding site?
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Transcriptional control signals of a eukaryotic protein-coding gene
TL;DR: Transcriptional control signals of a model eukaryotic protein-coding gene have been identified by a new procedure of in vitro mutagenesis that allows small clusters of nucleotide residues to be substituted in a site-directed manner without causing the addition or deletion of other sequences.
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A Decade of Riboswitches
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References
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Journal ArticleDOI
Regulatory Sequences Involved in the Promotion and Termination of RNA Transcription
Martin Rosenberg,Donald L. Court +1 more
Journal ArticleDOI
Termination Factor for RNA Synthesis
TL;DR: A new protein has been isolated from E. coli which causes specific termination and release of RNA during synthesis in vitro and has been given the name ρ-factor.
Book
The Bacteriophage Lambda.
TL;DR: No wonder you activities are, reading will be always needed, it is not only to fulfil the duties that you need to finish in deadline time, but also to encourage your mind and thoughts.
Journal ArticleDOI
Control of Transcription Termination
Sankar Adhya,Max E. Gottesman +1 more
TL;DR: The author revealed that RNA polymerase mutations located at the Site of Termination Site are linked to RHO mutations, and that pN acts at Many Sites and recognition Specificity of pN is recognized.
Journal ArticleDOI
The relationship between function and DNA sequence in an intercistronic regulatory region in phage λ
TL;DR: The potential molecular interactions and structural overlaps of these control signals apparently couple the regulation of the decision between lytic and lysogenic growth patterns by phage λ.