Azadirachta indica aqueous leaf extracts ameliorates coccidiosis in broiler chickens experimentally infected with Eimeria oocysts
ThankGod E. Onyiche,Jurbe G. Gotep,James T. Tanko,Grace O. Ochigbo,Harrison Anaezichukwuolu Ozoani,Vecheusi Zennobia Viyoff,Banenat B. Dogonyaro,M. S. Makoshi,Hauwa Kinjir,Oriel M. M. Thekisoe,A. A. Atiku,David Shamaki,Issa A. Muraina +12 more
- Vol. 13
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TLDR
In this article, the authors evaluated the ameliorative and therapeutic potentials of aqueous leaves extract of A. indica on some biological parameters such as weight gain, oocyst count, haematology, some biochemical and oxidative stress markers in broiler chicks experimentally infected with Eimeria oocytest.Abstract:
Attention has recently been focused on the protective effect of naturally occurring antioxidants in biological systems against parasites. Available evidence suggests that Azadirachta indica has good antioxidant ability as well as promising potentials in the management of parasitism. Therefore, this study evaluated the ameliorative and therapeutic potentials of aqueous leaves extract of A. indica on some biological parameters such as weight gain, oocyst count, haematology, some biochemical and oxidative stress markers in broiler chicks experimentally infected with Eimeria oocyst. Phytochemical analysis of A. indica revealed the presence of tannins, saponins, cardiac glycosides, alkaloids, flavonoids, and steroids. We observed a dose dependent mean weight gained in the treated groups compared with the negative control. The aqueous leaves extract of A. indica demonstrated an inhibitory effect on the shedding of oocyst in faeces of broiler chicks with up to 87.44% in the 800 mg/kg. The extract did not have significant effects on the RBCs, PCV and Hb concentrations in all the treatment groups compared to the negative control. The heterophils decreased in a dose dependent manner similar to the heterophils/lymphocyte ratio as compared to the negative control. Furthermore, the extract had hepato- and nephron-protective potentials by ameliorating markers of liver and kidney function such as ALT, AST, albumin, direct bilirubin, total bilirubin, and urea. Finally, the extract had good antioxidant ability by decreasing the MDA levels and increasing the levels of SOD, GSH and catalase when compared to the negative control giving further credence to support the folkloric application of the plant in the management of parasitic infections.read more
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Journal ArticleDOI
Methanolic extract of neem (Azadirachta indica) leaves mitigates experimentally induced coccidiosis challenge in Japanese quails
Rabia Ishaq,Naila Chand,Rifat Ullah Khan,Muhammad Nawaz Saeed,Vito Laudadio,Vincenzo Tufarelli +5 more
TL;DR: In this paper , a total of 150 male Japanese quails were equally assigned to five experimental treatments as follows: control (basal diet only), negative control (Eimeria challenged), amprolium treated, 130 mg/l methanolic extracts of neem leaves (NMLE 130), and 190´1´2´4´5´6´8´9´1''m methanol extracts of NEEM leaves(NMLE 190), and all the E. tenella-infected quail were orally dosed with sporulated oocysts.
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Biosynthesized selenium nanoparticles to rescue coccidiosis-mediated oxidative stress, apoptosis and inflammation in the jejunum of mice
Rewaida Abdel-Gaber,Maysar Abu Hawsah,Tahani T. Al-Otaibi,Ghada Alojayri,Esam M. Al-Shaebi,Osama B. Mohammed,Manal F. El-Khadragy,Saleh Al-Quraishy,Mohamed A. Dkhil +8 more
TL;DR: In this article , Bio-SeNPs were used to treat Eimeria papillata infection in the jejunal tissue, which significantly reduced body weight, oxidative stress, and inflammatory and apoptotic indicators.
Journal ArticleDOI
Evaluation of Anticoccidial Activity of Citrus aurantium L. Ethanolic Leaf Extract against Experimental Eimeria tenella Infection in Broiler Chickens (Gallus gallus domesticus)
Abubakar Ishaq,Dahiru Sani,Shuaibu Ahijo Abdullahi,Kelvin Olutimilehin Jolayemi,A.A Ebbo,I. D. Jatau,Ibrahim Madu Katsallah Gadzama +6 more
TL;DR: In this article , C. aurantium leaves were collected, authenticated, pulverized and extracted using ethanol and the results showed that treatment with ethanolic leaf extract of C.aurantium dose-dependently decreased the Eimeria tenella shedding, increase body weight, improved caecal lesion and significantly increased the PCV, TRBC and Hb concentration.
Journal ArticleDOI
Botanicals: A promising approach for controlling cecal coccidiosis in poultry
TL;DR: In this article , the authors present a review of the plants that have the potential to act as antic-occidials and explain the mode of action of different compounds found within them.
Journal ArticleDOI
Effects of Herbal Medicine in the Treatment of Poultry Coccidiosis
TL;DR: A review of the potential benefits and limitations of using herbal medicines as an alternative to conventional treatments for poultry coccidiosis is presented in this paper . But, the review is limited to poultry.
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