Journal ArticleDOI
Bacteriophage P2: Interaction with phage lambda and with recombination-deficient bacteria
TLDR
It is proposed that the λ Spi+ products convert recA−recB+ bacteria to RecB− phenocopies, as though the Spi- products could convert a recB+ host to a RecB+ phenocopy.About:
This article is published in Virology.The article was published on 1971-11-01. It has received 51 citations till now. The article focuses on the topics: Bacteriophage P2 & Lysogenic cycle.read more
Citations
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Journal ArticleDOI
A comprehensive molecular map of bacteriophage lambda.
TL;DR: In this article, physical and genetic mapping of deletion mutations has been correlated with the available molecular sizes of the λ gene products and the DNA base sequence to construct a comprehensive molecular map of the phage λ genome.
Journal ArticleDOI
Conditional Lethality of recA and recB Derivatives of a Strain of Escherichia coli K-12 with a Temperature-Sensitive Deoxyribonucleic Acid Polymerase I
M. Monk,J. Kinross +1 more
TL;DR: The results suggest that the primary lesion in these double mutants is not in DNA replication per se, and there is extensive DNA degradation.
Journal ArticleDOI
Replication of bacteriophage λ DNA dependent on the function of host and viral genes: I. Interaction of red, gam and rec
Lynn W. Enquist,A. Skalka +1 more
TL;DR: It is concluded that concatemer formation, via replication or recombination, is an essential step in phage development.
Journal ArticleDOI
Mechanisms of genome propagation and helper exploitation by satellite phage P4.
TL;DR: The P4 particles are less stable to heat inactivation, unless their capsids are coated with a P4-encoded decoration protein (the psu gene product).
Journal ArticleDOI
Interaction of the recombination pathways of bacteriophage λ and its host Escherichia coli K12: Effects on exonuclease V activity
Richard C. Unger,Alvin J. Clark +1 more
TL;DR: Infection of recB+ host cells of Escherichia coli with lambda bacteriophage converts the cells to RecB− phenocopies, indicating that the effect of the gam+ product may be specific to exonuclease V.
References
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Journal ArticleDOI
Mutants of escherichia coli k-12 defective in dna repair and in genetic recombination
Paul Howard-Flanders,Lee Theriot +1 more
TL;DR: It is suggested that the process of recombination may be completed by local DNA repair synthesis on either side of the overlap and that certain of the enzymes involved may serve in both genetic recombination and in repair after irradiation.
Journal ArticleDOI
Characteristics of Some Multiply Recombination-Deficient Strains of Escherichia coli
Neil Willetts,Alvin J. Clark +1 more
TL;DR: It is concluded that in a Rec(+) strain, the recA(+) product acts to inhibit DNA breakdown determined by the recC(+) and recB(+) products.
Journal ArticleDOI
Growth abnormalities in Hfr derivatives of Escherichia coli strain C.
I. Sasaki,G. Bertani +1 more
TL;DR: From Escherichia coli strain c, made F+ by infection with the sex factor F normally carried by E. coli strain K-12, several Hfr strains were derived; among these, four were found which exhibited a defective growth pattern on minimal media at 37°.
Journal ArticleDOI
Endonuclease-I-deficient and ribonuclease I-deficient Escherichia coli mutants.
TL;DR: A method has been developed to select for Escherichia coli mutants which lack certain nucleases, and mutants deficient in endonuclease I or RNase I were essentially identical to wild-type with respect to their general biological properties.
Journal ArticleDOI
Biochemical and genetic studies of recombination proficiency in Escherichia coli. I. Enzymatic activity associated with recB+ and recC+ genes.
TL;DR: An adenosine triphosphate-dependent deoxyribonuclease activity has been detected in lysates of recB(+)recC(+) strains, and mutations in recB or recC lead to loss of this activity, suggesting that these two genes determine the nucleaseActivity.
Related Papers (5)
The Role of Recombination in Growth of Bacteriophage Lambda I. The Gamma Gene
Replication of bacteriophage λ DNA dependent on the function of host and viral genes: I. Interaction of red, gam and rec
Lynn W. Enquist,A. Skalka +1 more