Barriers to recruitment of rural patients in cancer clinical trials.
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TLDR
The findings specify the need for patient and physician education through community outreach programs and oncologists should be trained to discuss clinical trials and to address concerns regarding their availability, utility, and accessibility.Abstract:
Rates of clinical trial participation are lower among patients in rural areas. Oncologists should be trained to address patient concerns regarding clinical trial availability, utility, and accessibility.read more
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Journal ArticleDOI
Systematic Review and Meta-Analysis of the Magnitude of Structural, Clinical, and Physician and Patient Barriers to Cancer Clinical Trial Participation.
TL;DR: These findings emphasize the enormous need to address structural and clinical barriers to trial participation, which combined make trial participation unachievable for more than three of four cancer patients.
Journal ArticleDOI
The National Cancer Institute-American Society of Clinical Oncology Cancer Trial Accrual Symposium: Summary and recommendations
Andrea Denicoff,Worta McCaskill-Stevens,Stephen S. Grubbs,Suanna S. Bruinooge,Robert L. Comis,Peggy Devine,David M. Dilts,Michelle E. Duff,Jean G. Ford,Steven Joffe,Lidia Schapira,Kevin P. Weinfurt,Margo Michaels,Derek Raghavan,Ellen S. Richmond,Robin T. Zon,Terrance L. Albrecht,Michael A. Bookman,Afshin Dowlati,Rebecca A. Enos,Mona N. Fouad,Marjorie J. Good,William J. Hicks,Patrick J. Loehrer,Alan P. Lyss,Steven N. Wolff,Debra Wujcik,Neal J. Meropol +27 more
TL;DR: A combination of approaches addressing both the multifactorial nature of accrual challenges and the characteristics of the target population may be needed to improveAccrual to cancer clinical trials.
Journal ArticleDOI
Closing the Rural Cancer Care Gap: Three Institutional Approaches.
Laura A. Levit,Leslie Byatt,Alan P. Lyss,Electra D. Paskett,Kathryn Levit,Kelsey Kirkwood,Caroline Schenkel,Richard L. Schilsky +7 more
TL;DR: The experience of the 3 institutions featured in the article suggests that increasing rural patients' access to care requires expanding services and decreasing travel distances, mitigating financial burdens when insurance coverage is limited, opening avenues to clinical trial participation, and creating partnerships between providers and community leaders to address local gaps in care.
Journal ArticleDOI
Diversity and inclusion for the All of Us research program: A scoping review.
Brandy Mapes,Christopher S. Foster,Sheila V. Kusnoor,Marcia I. Epelbaum,Mona AuYoung,Gwynne Jenkins,Maria Lopez-Class,Dara Richardson-Heron,Ahmed Elmi,Karl Surkan,Robert M. Cronin,Consuelo H. Wilkins,Eliseo J. Pérez-Stable,Eric Dishman,Joshua C. Denny,Joni L. Rutter +15 more
TL;DR: This paper describes how the program assessed demographic characteristics of participants who have enrolled in other U.S. biomedical research cohorts to better understand which groups are traditionally represented or underrepresented in biomedical research.
Journal ArticleDOI
Social Media and the Adolescent and Young Adult (AYA) Patient with Cancer
TL;DR: The use of social media in AYA with cancer is described and some of the online resources for AYAs are highlighted, which have very high rates of social social media usage.
References
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Journal ArticleDOI
Systematic Review of Barriers to the Recruitment of Older Patients With Cancer Onto Clinical Trials
TL;DR: Specific clinical trials confined to older patients should be conducted to evaluate tumor biology, treatment tolerability, and the effect of comorbid conditions, and protocol designs need to stratify for age and be less restrictive with respect to exclusions on functional status,Comorbidity, and previous cancers, such that results are generalizable to Older patients.
Journal ArticleDOI
Prospective Evaluation of Cancer Clinical Trial Accrual Patterns: Identifying Potential Barriers to Enrollment
Primo N. Lara,Roger Higdon,Nelson Lim,Karen Kwan,Michael Tanaka,Derick H Lau,Theodore Wun,Jeanna L Welborn,Frederick J. Meyers,Scott D Christensen,Robert T. O'Donnell,Carol M. Richman,Sidney A. Scudder,Joseph Tuscano,David R. Gandara,Kit S. Lam +15 more
TL;DR: Barriers to cancer clinical trial accrual can be prospectively identified and addressed in the development and conduct of future studies, which may potentially lead to more robust clinical trials enrollment.
Journal ArticleDOI
How Sociodemographics, Presence of Oncology Specialists, and Hospital Cancer Programs Affect Accrual to Cancer Treatment Trials
Warren B. Sateren,Edward L. Trimble,Jeffrey Abrams,Otis W. Brawley,Nancy Breen,Leslie G. Ford,Mary S. McCabe,Richard Kaplan,M Smith,Richard Ungerleider,Michaele C. Christian +10 more
TL;DR: The number of oncologists and the presence of approved cancer programs both were significantly associated with increased accrual to clinical trials, and the highest observed accruals was in suburban counties.
Journal ArticleDOI
Barriers to Clinical Trial Participation by Older Women With Breast Cancer
Margaret Kemeny,Bercedis L. Peterson,Alice B. Kornblith,Hyman B. Muss,Judith Wheeler,Ellis Levine,Nancy L. Bartlett,Gini F. Fleming,Harvey J. Cohen +8 more
TL;DR: Age and stage were the only predictors of whether a patient was offered a trial in a multivariate analysis including comorbid conditions, and the physicians' perceptions about age and tolerance of toxicity were the greatest impediment to enrolling older women onto trials.