Journal ArticleDOI
Beneficial effects of humidified high flow nasal oxygen in critical care patients: a prospective pilot study
Benjamin Sztrymf,Jonathan Messika,Fabrice Bertrand,Dominique Hurel,Rusel Leon,Didier Dreyfuss,Jean-Damien Ricard +6 more
TLDR
HFNC has a beneficial effect on clinical signs and oxygenation in ICU patients with acute respiratory failure, and favorable results constitute a prerequisite to launching a randomized controlled study to investigate whether HFNC reduces intubation in these patients.Abstract:
Purpose
To evaluate the efficiency, safety and outcome of high flow nasal cannula oxygen (HFNC) in ICU patients with acute respiratory failure.read more
Citations
More filters
Journal ArticleDOI
High-flow oxygen through nasal cannula in acute hypoxemic respiratory failure.
Jean-Pierre Frat,Arnaud W. Thille,Alain Mercat,Christophe Girault,Stéphanie Ragot,Sébastien Perbet,Gwenaël Prat,Thierry Boulain,Elise Morawiec,Alice Cottereau,Jérôme Devaquet,Saad Nseir,Keyvan Razazi,Jean-Paul Mira,Laurent Argaud,Jean-Charles Chakarian,Jean-Damien Ricard,Xavier Wittebole,Stéphanie Chevalier,Alexandre Herbland,Muriel Fartoukh,Jean-Michel Constantin,Jean-Marie Tonnelier,Marc Pierrot,Armelle Mathonnet,Gaetan Beduneau,Celine Deletage-Metreau,Jean-Christophe M. Richard,Laurent Brochard,René Robert +29 more
TL;DR: In patients with nonhypercapnic acute hypoxemic respiratory failure, treatment with high-flow oxygen, standard oxygen, or noninvasive ventilation did not result in significantly different intubation rates, and there was a significant difference in favor of high- flow oxygen in 90-day mortality.
Journal ArticleDOI
An Index Combining Respiratory Rate and Oxygenation to Predict Outcome of Nasal High-Flow Therapy
Oriol Roca,Oriol Roca,Berta Caralt,Berta Caralt,Jonathan Messika,Jonathan Messika,Manuel Samper,Benjamin Sztrymf,Gonzalo Hernández,Marina García-de-Acilu,Jean Pierre Frat,Jean Pierre Frat,Jean Pierre Frat,Joan R. Masclans,Joan R. Masclans,Jean-Damien Ricard,Jean-Damien Ricard +16 more
TL;DR: In patients with pneumonia with acute respiratory failure treated with HFNC, ROX is an index that can help identify those patients with low and those with high risk for intubation.
Journal ArticleDOI
Failure of high-flow nasal cannula therapy may delay intubation and increase mortality
Byung Ju Kang,Younsuck Koh,Chae-Man Lim,Jin Won Huh,Seunghee Baek,Myongja Han,Hyun-Suk Seo,Hee Jung Suh,Ga Jin Seo,Eun Young Kim,Sang-Bum Hong +10 more
TL;DR: Failure of HFNC might cause delayed intubation and worse clinical outcomes in patients with respiratory failure and large prospective and randomized controlled studies on HFNC failure are needed to draw a definitive conclusion.
Journal ArticleDOI
Nasal high-flow versus Venturi mask oxygen therapy after extubation. Effects on oxygenation, comfort, and clinical outcome
Salvatore Maurizio Maggiore,Francesco Idone,Rosanna Vaschetto,Rossano Festa,Andrea Di Cataldo,Federica Antonicelli,Luca Montini,Andrea De Gaetano,Paolo Navalesi,Massimo Antonelli +9 more
TL;DR: Compared with the Venturi mask, NHF results in better oxygenation for the same set FiO2 after extubation, and use of NHF is associated with better comfort, fewer desaturations and interface displacements, and a lower reintubation rate.
Journal ArticleDOI
High-flow Oxygen Therapy in Acute Respiratory Failure
Joan R. Masclans,Oriol Roca +1 more
TL;DR: In this paper, a method has been described in which flows of up to 50 L/min are delivered through a nasal cannula with a heated humidifier that optimizes oxygen administration.
References
More filters
Journal ArticleDOI
Noninvasive ventilation for acute exacerbations of chronic obstructive pulmonary disease.
Laurent Brochard,Jordi Mancebo,Marc Wysocki,Frédéric Lofaso,Giorgio Conti,Alain Rauss,Gérald Simonneau,Salvador Benito,A. Gasparetto,François Lemaire +9 more
TL;DR: In selected patients with acute exacerbations of chronic obstructive pulmonary disease, noninvasive ventilation can reduce the need for endotracheal intubation, the length of the hospital stay, and the in-hospital mortality rate.
Journal ArticleDOI
Noninvasive Ventilation in Immunosuppressed Patients with Pulmonary Infiltrates, Fever, and Acute Respiratory Failure
Gilles Hilbert,Didier Gruson,Frédéric Vargas,Ruddy Valentino,G Gbikpi-Benissan,Michel Dupon,Josy Reiffers,J. P. Cardinaud +7 more
TL;DR: In selected immunosuppressed patients with pneumonitis and acute respiratory failure, early initiation of noninvasive ventilation is associated with significant reductions in the rates of endotracheal intubation and serious complications and an improved likelihood of survival to hospital discharge.
Journal ArticleDOI
Research in high flow therapy: mechanisms of action.
TL;DR: The proposed mechanisms behind the efficacy of high flow therapy via nasal cannula are reviewed, which include washout of nasopharyngeal dead space, attenuation of the inspiratory resistance associated with thenasopharynx, improvement in conductance and pulmonary compliance, mild distending pressure and reduction in energy expenditure for gas conditioning.
Journal Article
High-flow oxygen therapy in acute respiratory failure.
TL;DR: HFNC was better tolerated and more comfortable than face mask and was associated with better oxygenation and lower respiratory rate, which could have an important role in the treatment of patients with acute respiratory failure.
Journal ArticleDOI
High-flow Oxygen Therapy in Acute Respiratory Failure
Joan R. Masclans,Oriol Roca +1 more
TL;DR: In this paper, a method has been described in which flows of up to 50 L/min are delivered through a nasal cannula with a heated humidifier that optimizes oxygen administration.
Related Papers (5)
High-flow oxygen therapy in acute respiratory failure.
High-flow oxygen through nasal cannula in acute hypoxemic respiratory failure.
Jean-Pierre Frat,Arnaud W. Thille,Alain Mercat,Christophe Girault,Stéphanie Ragot,Sébastien Perbet,Gwenaël Prat,Thierry Boulain,Elise Morawiec,Alice Cottereau,Jérôme Devaquet,Saad Nseir,Keyvan Razazi,Jean-Paul Mira,Laurent Argaud,Jean-Charles Chakarian,Jean-Damien Ricard,Xavier Wittebole,Stéphanie Chevalier,Alexandre Herbland,Muriel Fartoukh,Jean-Michel Constantin,Jean-Marie Tonnelier,Marc Pierrot,Armelle Mathonnet,Gaetan Beduneau,Celine Deletage-Metreau,Jean-Christophe M. Richard,Laurent Brochard,René Robert +29 more