Bioprocess modelling for the design and optimization of lignocellulosic biomass fermentation
TLDR
Modelling relevant to lignocellulosic bioprocess including cell modelling based on kinetics, stoichiometry and integrative approaches and fermentation kinetic modelling for process performance assessment are discussed.Abstract:
Lignocellulosic feedstocks, which are currently under-exploited, can be used for the production of biofuels, such as ethanol, and for biorefinery applications to produce a variety of value-added products. Although bioconversion of lignocellulose by microbial or yeast fermentation have been reported, efficient and economical lignocellulosic fermentation process is still a challenge due to multiple process parameters involved for bioprocess design, optimization and scale-up. Bioprocess modelling strategies have been proven effective for achieving
high-production process* efficiency in yield, productivity or titer of desired product. Several types of bioprocess modelling for lignocellulosic application have been developed and successfully validated as a promising alternative for rapid design, optimization and scaling up of biomass-based process. This review aims to summarize the important development of bioprocess modelling for lignocellulosic bioprocess applications towards the success of biorefineries and bio-based economy. In particular, we discuss modelling relevant to lignocellulosic bioprocess including cell modelling based on kinetics, stoichiometry and integrative approaches and fermentation kinetic modelling for process performance assessment. An overview of these modelling approaches and their application for systematic design of efficient and economical lignocellulose-based bioprocesses are given.read more
Citations
More filters
Journal ArticleDOI
Microplastics accumulate fungal pathogens in terrestrial ecosystems
Gerasimos Gkoutselis,Stephan Rohrbach,Janno Harjes,Martin Obst,Andreas Brachmann,Marcus A. Horn,Gerhard Rambold +6 more
TL;DR: In this article, epiplastic mycobiomes from municipal plastic waste from Kenya were deciphered using ITS metabarcoding as well as a comprehensive meta-analysis, and visualised via scanning electron as well and confocal laser scanning microscopy.
Journal ArticleDOI
Production of cupcake-like dessert containing microbial biosurfactant as an emulsifier
Ivison Amaro da Silva,Bruno Oliveira de Veras,Beatriz Galdino Ribeiro,Jaciana S. Aguiar,Jenyffer Medeiros Campos Guerra,Juliana M. Luna,Leonie Asfora Sarubbo +6 more
TL;DR: The biosurfactant proved to be promising for application in foods low in antioxidants and did not show cytotoxic potential in the tested cell lines, and has potential forApplication in the food industry as an emulsifier for flour dessert.
Journal ArticleDOI
Review on anaerobic digestion models: Model classification & elaboration of process phenomena
TL;DR: A review of anaerobic digestion models for efficient biogas production can be found in this article , where a collective and comprehensive review approach has been undertaken to enable the evaluation of the interdependence of all processes, process factors, and process estimations and their individual, and interactive effects on AD.
Journal ArticleDOI
Lignin-modifying enzymes: a green and environmental responsive technology for organic compound degradation
Débora da Silva Vilar,Muhammad Bilal,Ram Naresh Bharagava,Ajay Kumar,Ashok Kumar Nadda,Giancarlo R. Salazar-Banda,Katlin I.B. Eguiluz,Luiz Fernando Romanholo Ferreira +7 more
Journal ArticleDOI
Use of spent coffee ground biochar as ambient PAHs sorbent and novel extraction method for GC-MS analysis
Wittaya Tala,Somporn Chantara +1 more
TL;DR: Production and characterization of biochar and its extraction parameters after PAHs adsorption were investigated and optimized, and an effective clean-up method for biochar was proposed.
References
More filters
Journal ArticleDOI
Hydrolysis of lignocellulosic materials for ethanol production: a review.
Ye Sun,Jiayang Cheng +1 more
TL;DR: Simultaneous saccharification and fermentation effectively removes glucose, which is an inhibitor to cellulase activity, thus increasing the yield and rate of cellulose hydrolysis, thereby increasing the cost of ethanol production from lignocellulosic materials.
Journal ArticleDOI
Inhibition of ethanol-producing yeast and bacteria by degradation products produced during pre-treatment of biomass.
TL;DR: The inhibitory effect on ethanol production by yeast and bacteria is presented and the inhibition of volumetric ethanol productivity was found to depend on the amount of methoxyl substituents and hence hydrophobicity (log P).
Journal ArticleDOI
Increased tolerance and conversion of inhibitors in lignocellulosic hydrolysates by Saccharomyces cerevisiae
João R. M. Almeida,Tobias Modig,Anneli Petersson,Bärbel Hahn-Hägerdal,Gunnar Lidén,Marie-Francoise Gorwa-Grauslund +5 more
TL;DR: Among the microorganisms that have been evaluated for lignocellulosic hydrolysate ethanol fermentation, the yeast Saccharomyces cerevisiae appears to be the least sensitive.
Journal ArticleDOI
A review of lignocellulose bioconversion using enzymatic hydrolysis and synergistic cooperation between enzymes--factors affecting enzymes, conversion and synergy.
J.S. Van Dyk,Brett I. Pletschke +1 more
TL;DR: This review examines the enzymes required to degrade various components of lignocellulose and the impact of pretreatments on the lignosic substrates and the enzyme required for degradation and the effect of and interaction between different hemicellulases on complex substrates.
Journal ArticleDOI
Applications of genome-scale metabolic reconstructions
TL;DR: This review examines the many uses and future directions of genome‐scale metabolic reconstructions, and highlights trends and opportunities in the field that will make the greatest impact on many fields of biology.