Campylobacter pyloridis and Gastritis

TLDR: The canaliculi of parietal cells were sometimes invaded, an occurrence suggesting that the organisms were acid tolerant; and in some specimens, infiltration with polymorphs, lymphocytes, and plasma cells was seen in association with the bacteria.

Abstract: Spiral bacteria had been observed in the stomachs of humans and animals by Bizzozero [2] and Salomon [3] at the turn of the century. The first human study was done by Doenges [4], who found the bacterium in 43 ^o of 242 stomachs from postmortem examinations and who described it as "a thick organism with only two or three spirals . . . occasionally within parietal cells," perhaps recognizing that it did not have the thin, multiple coils of the spirochetes. The canaliculi of parietal cells were sometimes invaded, an occurrence suggesting that the organisms were acid tolerant; and in some specimens, infiltration with polymorphs, lymphocytes, and plasma cells was seen in association with the bacteria.