Open Access
Cascade reactions in multicompartmentalized polymersomes
Ruud J. R. W. Peters,Maïté Marguet,S. Marais,Marco W. Fraaije,J.C.M. van Hest,Sébastien Lecommandoux +5 more
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TLDR
An original cofactor-dependent three-enzyme cascade reaction is performed, using either compatible or incompatible enzymes, which takes place across multiple compartments.About:
The article was published on 2013-01-01 and is currently open access. It has received 385 citations till now. The article focuses on the topics: Polymersome.read more
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Nanozymes: Classification, Catalytic Mechanisms, Activity Regulation, and Applications
TL;DR: This review systematically introduces the classification, catalytic mechanism, activity regulation as well as recent research progress of nanozymes in the field of biosensing, environmental protection, and disease treatments, etc. in the past years.
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Liposomes and polymersomes: a comparative review towards cell mimicking.
TL;DR: This work compares and contrast liposomes and polymersomes for a better a priori choice and design of vesicles and tries to understand the advantages and shortcomings associated with using one or the other in many different aspects.
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Hollow Nano- and Microstructures as Catalysts
Gonzalo Prieto,Harun Tüysüz,Nicolas Duyckaerts,Johannes Knossalla,Guang-Hui Wang,Ferdi Schüth +5 more
TL;DR: This review provides an updated and critical survey of the ever-expanding material architectures and applications of hollow structures in all branches of catalysis, including bio-, electro-, and photocatalysis.
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Enzymatic reactions in confined environments
TL;DR: Some of the general principles of enzymatic reactions confined on surfaces, at interfaces, and inside small volumes are discussed and some of the necessary future steps to improve fundamental understanding of these systems are critically evaluated.
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Bioinspired polymer vesicles and membranes for biological and medical applications
Cornelia G. Palivan,Roland Goers,Roland Goers,Adrian Najer,Xiaoyan Zhang,Anja Car,Wolfgang Meier +6 more
TL;DR: This work presents supramolecular polymer assemblies resulting from self-assembly of mostly amphiphilic copolymers either as 3D compartments either as polymersomes, PICsomes, peptosomes, or as planar membranes as candidates in applications ranging from drug delivery systems, up to artificial organelles, or active surfaces.
References
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Synthetic protein scaffolds provide modular control over metabolic flux
John E. Dueber,Gabriel C. Wu,G Reza Malmirchegini,G Reza Malmirchegini,Tae Seok Moon,Christopher J. Petzold,Christopher J. Petzold,Adeeti Ullal,Kristala L. J. Prather,Jay D. Keasling +9 more
TL;DR: In this article, synthetic protein scaffolds bearing interaction domains from metazoan signaling proteins were used to spatially recruit metabolic enzymes in a designable manner, and the modularity of these domains enabled them to optimize the stoichiometry of three mevalonate biosynthetic enzymes recruited to a synthetic complex.
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A vesicle bioreactor as a step toward an artificial cell assembly
TL;DR: The alpha-hemolysin pore protein from Staphylococcus aureus is expressed inside the vesicle to create a selective permeability for nutrients to solve the energy and material limitations and increase the capacity of the reactor.
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Respiratory metabolism: glycolysis, the TCA cycle and mitochondrial electron transport.
TL;DR: A wide range of molecular and biochemical strategies have been adopted to elucidate the functional significance of these interactions between mitochondrial function in the photosynthetic and photorespiratory processes, amino-acid biosynthesis and the regulation of cellular redox.
Journal Article
Synthesizing life : Paths to unforeseeable science & technology
TL;DR: Advances in directed evolution and membrane biophysics make the synthesis of simple living cells, if not yet foreseeable reality, an imaginable goal.
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CO2 concentrating mechanisms in cyanobacteria: molecular components, their diversity and evolution
Murray R. Badger,G. Dean Price +1 more
TL;DR: There are multiple carbonic anhydrases in many cyanobacteria, but, surprisingly, several cyanobacterial genomes appear to lack any identifiable CA genes.