Journal ArticleDOI
Catalytic and enantioselective α-functionalization of oxindoles through oxidative reactions with naphthoquinones.
Woon-Yew Siau,Wenjun Li,Fei Xue,Qiao Ren,Minghu Wu,Shaofa Sun,Haibing Guo,Xuefeng Jiang,Jian Wang +8 more
TLDR
Optically active 3,3-disubstituted oxindoles were obtained by a new organocatalyzed aerobic oxidative method as discussed by the authors, which was used to extract oxindole oxides.Abstract:
Optically active 3,3-disubstituted oxindoles are obtained by a new organocatalyzed aerobic oxidative method.read more
Citations
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All-carbon quaternary centers in natural products and medicinal chemistry: recent advances
Taotao Ling,Fatima Rivas +1 more
Journal ArticleDOI
Highly Enantioselective [3+2] Coupling of Indoles with Quinone Monoimines Promoted by a Chiral Phosphoric Acid
Li-Hua Liao,Chang Shu,Minmin Zhang,Yijun Liao,Xiao-Yan Hu,Yonghong Zhang,Zhi-Jun Wu,Wei-Cheng Yuan,Xiao-Mei Zhang +8 more
TL;DR: A large variety of benzofuroindolines were prepared in moderate to good yields and with generally excellent enantioselectivities (up to 99% ee).
Journal ArticleDOI
Recent Catalytic Asymmetric Syntheses of 3,3-Disubstituted Indolin-2-ones and 2,2-Disubstituted Indolin-3-ones
TL;DR: The literature on asymmetric catalytic methods for disubstituted oxindoles has been largely reviewed in the last few years as discussed by the authors, and this literature has been mainly focused on spirocyclic derivatives.
Journal ArticleDOI
Catalytic Enantioselective α-Arylation of Carbonyl Enolates and Related Compounds
TL;DR: Optically active α-arylation carbonyl units are widely present in a wide variety of drugs, bioactive natural products, and valuable pharmacologically active molecules.
Journal ArticleDOI
Catalytic asymmetric reactions and synthesis of quinones
Basavaprabhu Hosamani,Matheus F. Ribeiro,Eufrânio N. da Silva Júnior,Irishi N. N. Namboothiri +3 more
TL;DR: Asymmetric reactions and the synthesis of various quinones, carried out in the presence of chiral organocatalysts and metal-ligand complexes, are reviewed here.
References
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Journal ArticleDOI
Small-molecule H-bond donors in asymmetric catalysis.
Journal ArticleDOI
Enantioselective Michael Reaction of Malonates to Nitroolefins Catalyzed by Bifunctional Organocatalysts
TL;DR: Michael reaction of malonates to nitrooleolefins with chiral bifunctional organocatalysts, bearing both a thiourea and tertiary amino group, afforded Michael adducts with high yields and enantioselectivities.
Journal ArticleDOI
Catalytic Asymmetric Synthesis of Oxindoles Bearing a Tetrasubstituted Stereocenter at the C‐3 Position
Feng Zhou,Yun-Lin Liu,Jian Zhou +2 more
TL;DR: The catalytic asymmetric synthesis of the tetrasubstituted carbon stereocenter at the C-3 position of the oxindole framework integrates new synthetic methods and chiral catalysts.
Journal ArticleDOI
Asymmetric Syntheses of Oxindoleand Indole Spirocyclic Alkaloid Natural Products
Barry M. Trost,Megan K. Brennan +1 more
TL;DR: This review highlights the advances in the literature up to May2009 in the synthesis of spirocyclic indoline natural products, including bothenantioselective and diastereoselectives methods.
Journal ArticleDOI
Enantio- and Diastereoselective Michael Reaction of 1,3-Dicarbonyl Compounds to Nitroolefins Catalyzed by a Bifunctional Thiourea
TL;DR: A new class of bifunctional catalysts bearing a thiourea moiety and an amino group on a chiral scaffold bearing 3,5-bis(trifluoromethyl)benzene and dimethylamino groups was revealed to be highly efficient for the asymmetric Michael reaction of 1,3-dicarbonyl compounds to nitroolefins.
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