CATALYTIC ENANTIOSELECTION BY CHIRAL TRANSITION-METAL COMPLEXES. I. DEHYDROGENATION OF RACEMIC α-PHENYLETHANOL BY RuCl2(PPh3)3 AND (+)-NEOMENTHYLDIPHENYLPHOSPHINE
TLDR
The enantioselective dehydrogenation of racemic (R-(+) and S-(−)) α-phenylethanol by RuCl2(PPh3)3 and (+)-neomenthyldiphenylphosphine at 180°C showed constant ratios of kR Ω(kS) in the absence of benzalacetone.Abstract:
The enantioselective dehydrogenation of racemic (R-(+) and S-(−)) α-phenylethanol by RuCl2(PPh3)3 and (+)-neomenthyldiphenylphosphine at 180°C showed constant ratios of kR⁄kS in the absence of benzalacetone. The kR⁄kS value increased almost linearly with the benzalaceton concentration and decreased with the larger amounts of the chiral phosphine under the present reaction conditions.read more
Citations
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References
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Journal ArticleDOI
New complexes of ruthenium (II) and (III) with triphenylphosphine, triphenylarsine, trichlorostannate, pyridine and other ligands
T.A. Stephenson,G. Wilkinson +1 more
TL;DR: In this article, the interaction of triphenylphosphine, -arsine and -stibine with hydrated ruthenium trichloride in methanol leads to a variety of complexes such as [RuCl2(PPh3)4], [RuCL2(SbPh3]3], RuCl3(Pph3)2CH3OH, [RuC2(CPh3As, Ph3Sb, pyridine etc., with a carbonyl-containing solution] and the corresponding brom
Journal ArticleDOI
Solution structure and dynamics of five-coordinate d6 complexes
P. R. Hoffman,K. G. Caulton +1 more
Journal ArticleDOI
Studies on the constituents of umbelliferae plants—XI
TL;DR: The absolute configuration of (−)-3-butylphthalide (II) has been determined by two independent methods as discussed by the authors, and the configuration of cnidilide (I) is known.
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