Journal ArticleDOI
Ceramic composites as matrices and scaffolds for drug delivery in tissue engineering.
TLDR
The high density and slow biodegradability of ceramics is not beneficial for tissue engineering purposes, so macroporosity can be introduced often in combination with osteoinductive growth factors and cells to address these issues.About:
This article is published in Advanced Drug Delivery Reviews.The article was published on 2007-05-30. It has received 521 citations till now. The article focuses on the topics: Ceramic & Biodegradable polymer.read more
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Nanoscale hydroxyapatite particles for bone tissue engineering
Hongjian Zhou,Jaebeom Lee +1 more
TL;DR: This feature article looks afresh at nano-HAp particles, highlighting the importance of size, crystal morphology control, and composites with other inorganic particles for biomedical material development.
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Bioactive Glass and Glass-Ceramic Scaffolds for Bone Tissue Engineering
TL;DR: Current knowledge on porous bone tissue engineering scaffolds on the basis of melt-derived bioactive silicate glass compositions and relevant composite structures is reviewed and discussed.
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Polymeric Materials for Bone and Cartilage Repair
TL;DR: Current strategies in scaffold-guided tissue engineering approach, involving the most employed biodegradable polymers, either of natural or synthetic origin, will be reported underlying the role played by both material structure–property relationship and scaffold architecture.
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3D bioactive composite scaffolds for bone tissue engineering.
Gareth Turnbull,Jon Clarke,Frederic Picard,Frederic Picard,Philip Riches,Luanluan Jia,Fengxuan Han,Bin Li,Wenmiao Shu +8 more
TL;DR: This review will consider the ideal properties of bioactive composite 3D scaffolds and examine recent use of polymers, hydrogels, metals, ceramics and bio-glasses in BTE.
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Calcium phosphate ceramic systems in growth factor and drug delivery for bone tissue engineering: A review
Susmita Bose,Solaiman Tarafder +1 more
TL;DR: This review highlights some of the current drug and growth factor delivery approaches and critical issues using CaP particles, coatings, cements, and scaffolds towards orthopedic and dental applications.
References
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Porosity of 3D biomaterial scaffolds and osteogenesis.
TL;DR: New fabrication techniques, such as solid-free form fabrication, can potentially be used to generate scaffolds with morphological and mechanical properties more selectively designed to meet the specificity of bone-repair needs.
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Scaffolds in tissue engineering bone and cartilage.
TL;DR: Research on the tissue engineering of bone and cartilage from the polymeric scaffold point of view is reviews from a biodegradable and bioresorbable perspective.
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Properties of Osteoconductive Biomaterials: Calcium Phosphates
TL;DR: CaP biomaterials have outstanding properties: similarity in composition to bone mineral; bioactivity; ability to form bone apatitelike material or carbonate hydroxyapatite on their surfaces; and osteoconductivity (ability to provide the appropriate scaffold or template for bone formation).
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Novel bioactive materials with different mechanical properties.
TL;DR: The biomimetic process has been used to deposit nano-sized bone- like apatite on fine polymer fibers, which were textured into a three-dimensional knit framework, which is expected to ultimately lead to bioactive composites that have a bone-like structure and, hence,Bone-like mechanical properties.
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Alginate hydrogels as biomaterials.
TL;DR: Micro-CT images of bone-like constructs that result from transplantation of osteoblasts on gels that degrade over a time frame of several months leading to improved bone formation are presented.