Journal ArticleDOI
Chemical and X-ray crystallographic characterization of the reaction products in the 1,3-dipolar cycloaddition of diazomethane to p-toluquinone
TLDR
In this article, X-ray crystallographic analysis was employed in the characterization of 1,6-dimethyl-1-H-indazole-4,7-dione (4a), which was the major 1-N-methyl regioisomer in the methylation of the cycloaddition mixture 2 with diazomethane.About:
This article is published in Journal of Heterocyclic Chemistry.The article was published on 1983-09-01. It has received 7 citations till now. The article focuses on the topics: 1,3-Dipolar cycloaddition & Cycloaddition.read more
Citations
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Journal ArticleDOI
Synthesis of N-benzylated indole-, indazole- and benzotriazole-4,7-diones
TL;DR: In this paper, a three-step pathway was developed to access 1-benzyl-1H-indazole-4,7-dione (3) with a 73% overall yield.
Journal ArticleDOI
Synthesis of indazol-4,7-dione derivatives as potential trypanocidal agents
Ricardo A. Tapia,Claudia Carrasco,Scarlet Ojeda,Cristian O. Salas,Jaime A. Valderrama,Antonio Morello,Yolanda Repetto +6 more
TL;DR: In this paper, the synthesis of indazol-4,7-dione derivatives via 1,3-dipolar cycloaddition of diazomethane with 2,3dimethyl-1,4-benzoquinone (2) and 1,4naphthoquinone(7) followed by N-alkylation of the pyrazol nitrogen atom of the corresponding quinones (3) and (8) with methyl chloroacetate is described.
Journal ArticleDOI
Synthesis of heterocyclic nitrogen derivatives from aryl‐1,4‐benzoquinones
TL;DR: In this article, 2-aryl-3,6-bis(arylamino)-1,4-benzoquinones 2a-h with different acid chlorides, namely acetyl, phenylacetyl and chloroacetyl chloride, were obtained in the 1,3-dipolar cycloaddition of diazomethane to (1).
Journal ArticleDOI
Synthesis and modulation properties of imidazo[4,5-b]pyridin-7-one and indazole-4,7-dione derivatives towards the Cryptosporidium parvum CpABC3 transporter.
Waël Zeinyeh,Hexue Xia,Philippe Lawton,Sylvie Radix,Christelle Marminon,Pascal Nebois,Nadia Walchshofer +6 more
TL;DR: These compounds could thus act like some flavonoid derivatives, which can partly overlap both the nucleotide-binding site and the adjacent hydrophobic steroid-binding region of mammalian P-glycoproteins.
Journal ArticleDOI
Zur Synthese und Struktur derp-Indazolchinone und ihrer Methylierungsprodukte Untersuchungen über Chinone, 8. Mitt.
TL;DR: In this article, the 2-methyl derivatives of benz-indazolquinone were established by reaction of corresponding benzoquinones with 3-methylsydnon in the case of 4e,4g.
References
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Journal ArticleDOI
Meso-ionic compounds
Wilson Baker,W. D. Ollis +1 more
TL;DR: In this article, the currently known types of meso-ionic heterocycles, which can then be considered in relation to the total number of possibilities associated with certain structural conditions.
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646. Chemical and physical properties of some sydnones
D. Ll. Hammick,Denys J. Voaden +1 more
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Diazomethan-Abbau von Bis-α-naphthochinon
TL;DR: In 1.3dipolarer cycloaddition with Diazomethan as discussed by the authors, das Addukt zu Naphthindazolchinon-(4.9) and dessen 5.8-Dihydroxy-Derivat liefert erwartungsgemas zwei isomere N-MethylDerivate, von denen in beiden Fallen nur das eine bekannt war.
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The reaction of diazomethane with benzoquinones
TL;DR: The reaction of diazomethane with p-benzoquinone and several of its derivatives in the presence of an oxidizing agent leads to the formation of derivatives of isoindazole-4,7-quinone as mentioned in this paper.