Chemical constituents of Salacia elliptica (Celastraceae)
Lucienir Pains Duarte,Rute C. Figueiredo,Grasiely Faria de Sousa,Débora B. S. Soares,Salomão Bento Vasconcelos Rodrigues,Fernando C. Silva,Grácia Divina de Fátima Silva,Sidney Augusto Vieira Filho +7 more
TLDR
In this paper, the chemical structure and relative configuration of a new triterpene 1,3-dioxo-16α-hydroxyfriedelane (15) were established through 1H and 13C NMR including 2D experiments (HMBC, HMQC, COSY and NOESY).Abstract:
The chemical investigation of Salacia elliptica allowed to the isolation of 20 constituents: two polyols, one xanthone, a mixture of long chain hydrocarbons, one carboxylic acid, one polymer, two steroidal compounds, one aromatic ester and eleven pentacyclic triterpenes. These triterpenes include 3β-stearyloxy-oleanane, 3β-stearyloxy-ursane, one seco-friedelane, and eight compounds of the friedelane serie. The chemical structure and the relative configuration of a new triterpene 1,3-dioxo-16α-hydroxyfriedelane (15) were established through 1H and 13C NMR including 2D experiments (HMBC, HMQC, COSY and NOESY) and herein reported for the first time.read more
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Chemical and Biological Research on Herbal Medicines Rich in Xanthones
Jingya Ruan,Chang Zheng,Yanxia Liu,Lu Qu,Haiyang Yu,Lifeng Han,Yi Zhang,Yi Zhang,Tao Wang,Tao Wang +9 more
TL;DR: This paper summarizes the plant resources, bioactivity and the structure-activity relationships (SARs) of xanthones from references published over the last few decades, which may be useful for new drug research and development onxanthones.
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In vitro antileishmanial, antiplasmodial and cytotoxic activities of a new ventiloquinone and five known triterpenes from Parinari excelsa.
Barthélemy Attioua,Dodehe Yeo,Latifou Lagnika,Ramiarantsoa Harisolo,Cyril Antheaume,Bernard Weniger,Marcel Kaiser,Annelise Lobstein,Catherine Vonthron-Sénécheau +8 more
TL;DR: The findings demonstrated that the constituents of P. excelsa stem bark have in vitro antiplasmodial and antileishmanial activities.
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Structure, histochemistry and phytochemical profile of the bark of the sobol and aerial stem of Tontelea micrantha (Celastraceae - Hippocrateoideae)
Maria Olívia Mercadante-Simões,Hellen Cássia Mazzottini-dos-Santos,Lays Araújo Nery,Perácio Rafael Bueno Ferreira,Leonardo Monteiro Ribeiro,Vanessa de Andrade Royo,Dario Alves de Oliveira +6 more
TL;DR: The similarities between these two organs indicate that the aerial stem bark has potential medicinal use and represents a plausible alternative to harvesting the sobol, which could contribute to the preservation of natural populations of this species.
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Unravelling the names, origins and chemistry of “muthis” used for male sexual disorders in KwaZulu-Natal, South Africa
TL;DR: This research shows for the first time that the major plant sources for these preparations are three plants from the genus Eriosema, which raises the question whether the quinone methides, and particularly pristimerin, have hitherto untested aphrodisiac-like properties, or whether unknown minor components in the plant are responsible for perceived sex-related activity.
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Microbiological evaluation of isolated compounds from the bark of Maytenus guianensis Klotzsch ex Reissek (Celastraceae)
Renato Abreu Lima,Fernanda Bay-Hurtado,Dionatas Ulises de Oliveira Meneguetti,João Bezerra Facundo,Júlio Sancho Linhares Teixeira Militão,Najla Benevides Matos,Valdir Alves Facundo +6 more
TL;DR: Os resultados sinalizam o potencial antimicrobiano dessa planta, podendo ser promissoras para estudos de desenvolvimento de novos farmacos sendo relevante a continuidade destes ensaios com outras cepas de bacterias.