Open AccessJournal Article
Chloroquine and fansidar resistance of Plasmodium falciparum now also in Ghana
TLDR
The authors report on the occurrence of chloroquine- and fansidar-resistant Plasmodium falciparum strains and draw the necessary conclusions for recommendations with regard to the prevention of life-endangering tropical malignant malaria.Abstract:
The authors report on the occurrence of chloroquine- and fansidar-resistant Plasmodium falciparum strains. From their results the authors draw the necessary conclusions for recommendations with regard to the prevention of life-endangering tropical malignant malaria.read more
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Journal ArticleDOI
High Prevalence of Markers for Sulfadoxine and Pyrimethamine Resistance in Plasmodium falciparum in the Absence of Drug Pressure in the Ashanti Region of Ghana
Florian Marks,Jennifer Evans,Christian Meyer,Edmund N. L. Browne,Christa Flessner,Vera von Kalckreuth,Teunis A. Eggelte,Rolf D. Horstmann,Jürgen May +8 more
TL;DR: A high frequency of CQ, PYR, and SDX resistance markers was observed, whereby, as a weak trend, the frequency was higher in 2003, and the quintuple combination of three pfdhfr mutations and two pFDhps mutations has previously been recognized to be the most important determinant of PYR-SDX resistance.
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Monitoring antifolate resistance in intermittent preventive therapy for malaria
TL;DR: The relationship between resistance mutations and SP-IPT within target populations in the context of monitoring and informing implementation of this intervention is reviewed.
Journal ArticleDOI
Contrasting Asymptomatic and Drug Resistance Gene Prevalence of Plasmodium falciparum in Ghana: Implications on Seasonal Malaria Chemoprevention
Cheikh Cambel Dieng,Lauren Gonzalez,Kareen Pestana,Shittu B. Dhikrullahi,Linda E. Amoah,Yaw A. Afrane,Eugenia Lo +6 more
TL;DR: A baseline for monitoring P. falciparum prevalence and resistance in response to SMC over time is established and TARE-2 serves as a more sensitive molecular marker for detecting submicroscopic asymptomatic infections in high and low transmission settings.
Journal ArticleDOI
HIV-1 Impact on Malaria Transmission: A Complex and Relevant Global Health Concern.
TL;DR: In this paper, the authors summarized evidence surrounding gametocyte production in Plasmodium falciparum and the development factors and the consequential impact that HIV-1 has on malaria parasite transmission.
Dissertation
IN-VITRO AND MOLECULAR STUDIES ON THE RESISTANCE P. falciparum TO ANTI-MALARIAL DRUGS IN OGUN STATE, SOUTHWESTERN NIGERIA
TL;DR: High prevalence of falciparum malaria was recorded in children 1-5 years while the same group also had the highest parasitaemia of 1080, and all the isolates tested were sensitive to Quinine, Mefloquine and Artesunate.