Journal ArticleDOI
Cleavage reactions with 4-substituted isoxazolin-5-ones
TLDR
In this article, the exocyclic double bond in 4-arylidene-3-methylisoxazolin-5-ones (IV) undergoes addition reactions with Grignard reagents and with aromatic hydrocarbons in the presence of aluminium chloride.About:
This article is published in Tetrahedron.The article was published on 1963-01-01. It has received 8 citations till now. The article focuses on the topics: Aluminium chloride & Phenylhydrazine.read more
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Unusual Approach to Branched 3-Alkynylamides and to 1,5-Dihydropyrrol-2-ones
TL;DR: Rare carboxamide branched alkynes such as 11a can be readily obtained by reaction of the electrophilic 4-alkylidene isoxazolinones with isocycanides followed by nitrosative cleavage of the heterocyclic ring.
Journal ArticleDOI
Isoxazole Chemistry Since 1963
Basil J. Wakefield,D.J. Wright +1 more
TL;DR: In this article, the development in the chemistry of isoxazoles is discussed, including further application of the cycloaddition of nitrile oxides in the synthesis of oxides, the use of oxoxazolium salts in peptide synthesis, syntheses involving the products of reductive cleavage of is oxazoles as intermediates, and annelation reactions via deprotonation of alkylisoxazole.
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Ring opening reaction of the pyridinium salt of 4-nitro-3-isoxazolin-5-one: A preparation of trifunctionalized methane derivatives
TL;DR: The ring cleavage of the pyridinium salt of 4-nitro-3-isoxazolin-5-one 1 was found to proceed under mild basic conditions and to give cyano-aci -nitroacetates 2 in quantitative yields as discussed by the authors.
Journal ArticleDOI
Chemistry of 5(2H)‐isoxazolones: Novel conversion of positional isomers
TL;DR: In this paper, 4-substituted-benzyl-3-methyl-5(2H)-isoxazolone derivatives have been observed for reaction with manganic acetate and pyridinium chlorochromate.
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Reaktionen mit Δ2‐Thiazolinonen‐(5), I. Verhalten von 2‐Alkoxy‐ und 2‐Alkylmercapto‐Derivaten gegenüber Aminen und Grignard‐Reagenzien
TL;DR: In this paper, the authors describe the behaviour of 2-alkylmercapto and 2-Alkoxy derivatives with respect to Amines and Grignard Reagents in the presence of aralkyl amines.
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Action of Grignard Reagents. XIV.1 Action of Organomagnesium Compounds on 1-Phenyl-3-methyl-4-arylidene-5-pyrazolones. Their Behavior toward Aromatic Secondary Amines and Aromatic Thiols
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