Journal ArticleDOI
Clinical Heterogeneity of Interstitial Lung Disease in Polymyositis and Dermatomyositis Patients With or Without Specific Autoantibodies.
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TLDR
MDA5‐ILD was associated with severe pulmonary manifestations, poor response to treatment and aggravated prognosis, and the ARS‐ILD group had favorable treatment response and prognosis.About:
This article is published in The American Journal of the Medical Sciences.The article was published on 2018-01-01. It has received 30 citations till now. The article focuses on the topics: Dermatomyositis & Polymyositis.read more
Citations
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Journal ArticleDOI
Identification of Three Different Phenotypes in Anti–Melanoma Differentiation–Associated Gene 5 Antibody–Positive Dermatomyositis Patients: Implications for Prediction of Rapidly Progressive Interstitial Lung Disease
Lingxiao Xu,Hanxiao You,Lei Wang,Chengyin Lv,Fenghong Yuan,Ju Li,Min Wu,Zhanyun Da,Hua Wei,Wei-Hong Yan,Lei Zhou,Songlou Yin,D-M Zhou,Jian Wu,Yan Liu,Dinglei Su,Zhichun Liu,Lin Liu,Longxin Ma,Xiaoya Xu,Y. Zang,Huijie Liu,Tianli Ren,Fang Wang,Yan Du,Jing Xue,Miaojia Zhang,Wenfeng Tan +27 more
TL;DR: Cluster analysis identified 3 distinct clinical patterns and outcomes in a large cohort of anti-MDA5+ DM patients, which may help physicians to improve the efficacy of clinical decisions.
Journal ArticleDOI
Palmar erythema and palmar papules as predictors for dermatomyositis-related acute/subacute interstitial lung disease: a retrospective study.
TL;DR: Wang et al. as discussed by the authors investigated the association between clinical features of Dermatomyositis (DM) and interstitial lung disease (ILD) in 207 patients with DM and analyzed the high-risk factors for ILD.
Journal ArticleDOI
Peripheral lymphocyte count defines the clinical phenotypes and prognosis in patients with anti‐MDA5‐positive dermatomyositis
Qiwen Jin,Lijun Fu,Hongxia Yang,Xi-xue Chen,Sang Lin,Zheng-Bo Huang,Bao-Xiang Gao,Xiaolan Tian,Xiaoming Shu,Xin Lu,Guochun Wang,Qinglin Peng +11 more
TL;DR: In this article , the role of peripheral lymphocyte count in phenotyping and prognosis prediction in dermatomyositis (DM) patients with anti-MDA5 antibodies was explored.
Journal ArticleDOI
Pathological Roles of Pulmonary Cells in Acute Lung Injury: Lessons from Clinical Practice
TL;DR: In this paper , a review of lung high-resolution computed tomography and lung histopathology is presented, focusing on majorly damaged cells in each disease and treatments that should be immediately initiated in clinical practice for each disease.
Book ChapterDOI
Myositis-Associated Interstitial Lung Disease
TL;DR: Patients with rapidly progressive ILD are at increased risk for death and should be treated aggressively and additional poor prognostic markers include the presence of antisynthetase antibodies other than Jo-1, MDA5 antibody, elevated CRP and ESR, advanced age, and elevated ferritin.
References
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Journal ArticleDOI
Polymyositis and dermatomyositis (first of two parts)
Anthony Bohan,James B. Peter +1 more
TL;DR: (First of Two Parts)
Journal ArticleDOI
An Official American Thoracic Society/European Respiratory Society Statement: Update of the International Multidisciplinary Classification of the Idiopathic Interstitial Pneumonias
William D. Travis,Ulrich Costabel,David M Hansell,Talmadge E. King,David A. Lynch,Andrew G. Nicholson,Christopher J. Ryerson,Jay H. Ryu,Moisés Selman,Athol U. Wells,Jurgen Behr,Demosthenes Bouros,Kevin K. Brown,Thomas V. Colby,Harold R. Collard,Carlos Robalo Cordeiro,Vincent Cottin,Bruno Crestani,Marjolein Drent,Rosalind F. Dudden,Jim Egan,Kevin R. Flaherty,Cory M. Hogaboam,Yoshikazu Inoue,Takeshi Johkoh,Dong Soon Kim,M Kitaichi,James E. Loyd,Fernando J. Martinez,Jeffrey L. Myers,Shandra Protzko,Ganesh Raghu,Luca Richeldi,Nicola Sverzellati,Jeffrey J. Swigris,Dominique Valeyre +35 more
TL;DR: This update is a supplement to the previous 2002 IIP classification document and outlines advances in the past decade and potential areas for future investigation.
Journal ArticleDOI
Would a new name hasten the acceptance of amyopathic dermatomyositis (dermatomyositis siné myositis) as a distinctive subset within the idiopathic inflammatory dermatomyopathies spectrum of clinical illness
TL;DR: The Master said, "If names are not correct, language is not in accordance with the truth of things, affairs cannot be carried out to success, therefore a superior man considers it necessary that the names he uses be spoken appropriately, what the superior man requires, is just that in his words there may be nothing incorrect as mentioned in this paper.
Journal ArticleDOI
Clinical manifestation and prognostic factor in anti-melanoma differentiation-associated gene 5 antibody-associated interstitial lung disease as a complication of dermatomyositis
Takahisa Gono,Yasushi Kawaguchi,Takashi Satoh,Masataka Kuwana,Yasuhiro Katsumata,Kae Takagi,Ikuko Masuda,Akiko Tochimoto,Sayumi Baba,Yuko Okamoto,Yuko Ota,Hisashi Yamanaka +11 more
TL;DR: Both serum ferritin and anti-MDA5 antibody are powerful indicators for the early diagnosis of A/SIP with DM and Ferritin also predicts disease severity and prognosis for patients with anti-mda5 antibody.
Journal ArticleDOI
Anti-MDA5 and anti-TIF1-γ antibodies have clinical significance for patients with dermatomyositis
TL;DR: Anti-MDA5 and anti-TIF1-gamma antibodies were detected based on their ability to immunoprecipitate biotinylated recombinant MDA5, and were closely associated with life-threatening complications in DM.