Journal ArticleDOI
Clinical significance of human sperm-zona pellucida binding
TLDR
Sperm morphology and hyperactivated motility showed a high correlation with the capacity of sperm to achieve tight binding to the ZP, providing additional support for the use of this functional bioassay in the decision-making process within the assisted reproduction setting.About:
This article is published in Fertility and Sterility.The article was published on 1997-06-01. It has received 83 citations till now. The article focuses on the topics: Sperm motility & Intracytoplasmic sperm injection.read more
Citations
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Journal ArticleDOI
Analysis of DNA fragmentation, plasma membrane translocation of phosphatidylserine and oxidative stress in human spermatozoa
TL;DR: Spermatozoa from infertile men display translocation of membrane phosphatidylserine as diagnosed by annexin V positive staining, and there is a relationship between DNA damage and oxidative stress.
Journal ArticleDOI
Defective sperm–zona pellucida interaction: a major cause of failure of fertilization in clinical in-vitro fertilization
De Yi Liu,H. W. G. Baker +1 more
TL;DR: In this paper, sperm-zona pellucida binding and penetration were assessed on oocytes that failed to fertilize from couples with >/=3 oocytes treated by standard in-vitro fertilization (IVF).
Journal ArticleDOI
Proteomic changes in mammalian spermatozoa during epididymal maturation.
TL;DR: At least in rodent species, activation of sperm mitochondria appears to be a particularly important part of epididymal maturation.
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Failed fertilization: is it predictable?
Neal G. Mahutte,Aydin Arici +1 more
TL;DR: This review critically examines the ability of screening tests to predict fertilization failure in sperm injection cycles and finds that screening tests are likely to be inaccurate in cases of failed fertilization.
Journal ArticleDOI
Sperm selection in natural conception: what can we learn from Mother Nature to improve assisted reproduction outcomes?
TL;DR: The value of sperm selection is examined to see how much guidance for ART can be gleaned from the natural selection processes in vivo as well as recent developments in in vitro selection and preparation methods.
References
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Journal ArticleDOI
Sperm morphologic features as a prognostic factor in in vitro fertilization.
Thinus F. Kruger,Roelof Menkveld,F. S. H. Stander,Carl Lombard,Jacobus P. Van der Merwe,Johannes A. van Zyl,Karen Smith +6 more
TL;DR: In this article, the authors conducted a prospective study in women with bilateral tubal damage to determine whether there is a prognostic value in the percentage normal sperm morphologic features in a human in vitro fertilization (IVF) program.
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Predictive value of abnormal sperm morphology in in vitro fertilization
Thinus F. Kruger,Anibal A. Acosta,Anibal A. Acosta,K.F. Simmons,K.F. Simmons,R.J. Swanson,R.J. Swanson,J.F. Matta,J.F. Matta,Sergio Oehninger,Sergio Oehninger +10 more
TL;DR: By evaluating sperm morphology with the proposed strict criteria, its predictive value in in vitro fertilization is enhanced.
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The hemizona assay (HZA): development of a diagnostic test for the binding of human spermatozoa to the human hemizona pellucida to predict fertilization potential * † ‡
Lani J. Burkman,Charles C. Coddington,Daniel R. Franken,Thinus F. Kruger,Zev Rosenwaks,Gary D. Hodgen +5 more
TL;DR: Sperm from fertile men exhibited significantly higher binding capacity to hemizonae compared with sperm from men who had fertilization failure during in vitro fertilization (IVF) treatment, demonstrating that the HZA may be a useful diagnostic tool in male infertility evaluations.
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Corrective measures and pregnancy outcome in in vitro fertilization in patients with severe sperm morphology abnormalities
Sergio Oehninger,Anibal A. Acosta,Mahmood Morshedi,Lucinda L. Veeck,R. James Swanson,Kathryn F. Simmons,Zev Rosenwaks +6 more
TL;DR: It is concluded that patients with severe sperm head abnormalities have a lower ability to establish successful pregnancies, even though fertilization may be achieved.
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Characterization of hyperactivated motility by human spermatozoa during capacitation: comparison of fertile and oligozoospermic sperm populations.
TL;DR: The incidence of hyperactivated movements by fertile and oligozoospermic spermatozoa could be significantly increased after exposure to various motility stimulants.